Results 51 to 60 of about 43,144 (243)

Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

open access: yesPLoS ONE, 2011
Sera from 25 metastatic breast cancer patients and 25 healthy controls were subjected to affinity chromatography using immobilized galectin-1. Serum from the healthy subjects contained on average 1.2 mg per ml (range 0.7-2.2) galectin-1 binding ...
Michael C Carlsson   +11 more
doaj   +1 more source

Envelope-receptor interactions in Nipah virus pathobiology. [PDF]

open access: yes, 2007
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core   +1 more source

Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3 [PDF]

open access: yes, 2009
A breakdown in intestinal homeostasis results in inflammatory bowel diseases including coeliac disease and allergy. Galectins, evolutionarily conserved beta-galactoside-binding proteins, can modulate immune-epithelial cell interactions by influencing ...
Ahmed, H.   +8 more
core   +3 more sources

Galectin genes: regulation of expression. [PDF]

open access: yes, 2002
In this review we have summarized the more recent studies on the expression of mammalian galectins. One interesting observation that can be made is that in most of microarrays and/or differential display analysis performed in recent years one or more ...
BRUNI, CARMELO BRUNO   +3 more
core   +1 more source

Nanoclustering as a dominant feature of plasma membrane organization [PDF]

open access: yes, 2014
Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra   +4 more
core   +10 more sources

Galectin-1 reduces the severity of dextran sulfate sodium (DSS)-induced ulcerative colitis by suppressing inflammatory and oxidative stress response

open access: yesBiomolecules & Biomedicine, 2020
Ulcerative colitis is an inflammatory bowel disease that affects a large number of people around the world. Galectin-1 is a β-galactoside-binding lectin with a broad range of biological activities.
Pelin Arda-Pirincci, Guliz Aykol-Celik
doaj   +1 more source

Galectins in Chagas Disease: A Missing Link Between Trypanosoma cruzi Infection, Inflammation, and Tissue Damage

open access: yesFrontiers in Microbiology, 2022
Trypanosoma cruzi, the protozoan parasite causative agent of Chagas disease, affects about seven million people worldwide, representing a major global public health concern with relevant socioeconomic consequences, particularly in developing countries ...
Carolina V. Poncini   +5 more
doaj   +1 more source

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

open access: yes, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Akos Horvath   +35 more
core   +1 more source

Functions of cell surface galectin-glycoprotein lattices [PDF]

open access: yes, 2007
Programmed remodeling of cell surface glycans by the sequential action of specific glycosyltransferases can control biological processes by generating or masking ligands for endogenous lectins. Galectins, a family of animal lectins with affinity for beta-
Jackson, Shawn S.   +3 more
core   +1 more source

Galectin-1 is a poor prognostic factor in patients with glioblastoma multiforme after radiotherapy

open access: yesBMC Cancer, 2018
Background Galectin-1, a radioresistance marker, was found in our previous study to be a prognostic factor for cervical cancer. The aim of current study is to determine the prognostic significance of the galectin-1 expression level in patients with ...
Shang-Yu Chou   +3 more
doaj   +1 more source

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