Results 101 to 110 of about 93,278,916 (238)
Journal of Surgical Oncology, EarlyView.ABSTRACT Liver transplantation (LT) is the definitive treatment for early hepatocellular carcinoma (HCC), based on established criteria. Pre‐transplant imaging occasionally underestimates the tumor burden or biological aggressiveness, leading to explant pathology that exceeds the projection criteria, such as Milan.
Serkan Sucu +2 more
wiley +1 more source
, 2019 Figure S2. Knockdown or overexpression of Galectin-1 in U251 or U87-MG cells. A. Galectin-1 was knocked down in U251 cell lines by SiRNA1â3. Galectin-1 siRNA2 and siRNA3 significantly reduced Galectin-1expression. B.
Shi Ma (217876) +12 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
Galectin-3 and cyclin D1 expression in non-small cell lung cancer
Journal of Experimental & Clinical Cancer Research, 2011 Introduction Lung cancer is a major cause of mortality and morbidity worldwide. Galectin-3 is multifunctional protein, which is involved in regulation of cell growth, cell adhesion, cell proliferation, angiogenesis and apoptosis.
Gołecki Marcin +4 more
doaj +1 more source
The Role of Galectin-3 in Th17 Differentiation
, 2010 第十七型輔助型T細胞 (T helper 17 cells, Th17 cells)，一個最近被大量研究的輔助型T細胞分支，在病理上被認為是導致自體免疫疾病的主要原因之一。在Th17的細胞分化以及生理作用上,之前研究中已提供許多方面深入的探討。然而在Th17細胞之負向調控機制上，則相對的較缺乏清楚的了解並且仍需要更多的研究。 在此研究中我們發現，與野生控制組相比，Galectin-3基因剔除之輔助型T細胞於體外分化時較容易且大量的分化至Th17細胞，伴隨著主要分泌之細胞激素( IL-17, IL-21 )
朱安翔, Chu, An-Hsiang
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Mucolipin TRP cation channel 1 (MCOLN1), also called TRPML1, drives the progression of various cancers and inhibits ferroptosis in a number of diseases. This study aimed to investigate whether MCOLN1 depletion regulates ferroptosis in gastric cancer and its molecular regulatory crosstalk with the AKT pathway.
Jing Wang +5 more
wiley +1 more source
Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis
, 2007 Inflammation of the subarachnoid and ventricular space contributes to the development of brain damage i.e. cortical necrosis and hippocampal apoptosis in pneumococcal meningitis (PM).
Bellac, Caroline L +15 more
core +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Galectin-3 as a Potential Target to Prevent Cancer Metastasis
, 2015 Interactions between two cells or between cell and extracellular matrix mediated by protein–carbohydrate interactions play pivotal roles in modulating various biological processes such as growth regulation, immune function, cancer metastasis, and ...
Dina M. M. AlSadek, Hafiz Ahmed
core +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source