Results 81 to 90 of about 18,236,146 (293)
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
(A) NbALFA staining of translocon associated YopD-ALFA in fixed cells. HeLa cells expressing myc-Rac1Q61L and GFP-galectin-3 were infected with WA-314-YopD-ALFA at an MOI of 50 for 50 min.
Maren Rudolph (11726318) +4 more
core +1 more source
Modulation of Animal Gut Health by Milk Oligosaccharide
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Korabiowska, M. +3 more
core +1 more source
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Objective Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL‐18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further IL‐18 ...
Greta Rogani +17 more
wiley +1 more source
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Data_Sheet_1_The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer.docx
Human cancer cells operate a variety of effective molecular and signaling mechanisms which allow them to escape host immune surveillance and thus progress the disease.
Svetlana S. Sakhnevych (6559877) +18 more
core +1 more source
Animal lectins as cell adhesion molecules [PDF]
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core +1 more source
A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source

