Results 151 to 160 of about 54,078 (242)

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Wound‐Healing Efficacy of Garcinia pedunculata Fruit Extract: In Vivo and In Silico Validation of Regenerative Mechanisms With Histological Analysis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study demonstrates that G. pedunculata fruit possesses potent wound‐healing activity, evidenced by accelerated wound contraction, reduced epithelialization time, enhanced fibroblast proliferation, increased collagen deposition, and improved neovascularization in both excision and burn models. ABSTRACT Garcinia pedunculata Roxb., traditionally used
Kazi Sanjida Tahrim, Md. Mushfiqur Rahman, Md. Sohanur Rahman, Mohammad Abu Sayem, Md. Safayat Hossen Momen, Tanvir Hasan, Md. Jahirul Islam Mamun, Md. Mahmudul Hasan   +7 more
wiley   +1 more source

Galectin-3 [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

MedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge, Yue‐Hua Li, Xuan Yu, Ming‐Yan Xing, Yi‐Hui Gu, Wei Wang, Jing‐Xuan Huang, Jun Liu, Hai‐Bing Zhang, Cheng‐Jiang Wei, Zhi‐Chao Wang, Qing‐Feng Li   +11 more
wiley   +1 more source

Galectin-3

Journal of the American College of Cardiology, 2019
Evangelos Oikonomou, Gerasimos Siasos, Dimitris Tousoulis   +2 more
openaire   +1 more source

Focus on Molecules: Galectin-3 [PDF]

Experimental Eye Research, 2011
Pablo, Argüeso, Noorjahan, Panjwani
openaire   +2 more sources

Nintedanib Lacks Efficacy in a Spirometry‐Confirmed and Bleomycin‐Induced Mouse Model of Idiopathic Pulmonary Fibrosis

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Nintedanib, a multitargeted tyrosine kinase inhibitor, is approved for idiopathic pulmonary fibrosis (IPF) for its ability to slow lung function decline. This study systematically evaluated the effects of nintedanib across three independent treatment intervention studies in the single‐dose bleomycin (BLEO) mouse model of IPF.
Jamal Bousamaki, Grzegorz Maciag, Asbjørn Graver Petersen, Stefanie H. Korntner, Stine Marie Jansen, Susanne E. Pors, Linn Salto Mamsen, Silas A. Rasmussen, Casper Gravesen Salinas, Louise Humle Kruse, Michael Feigh, Ulf Simonsen, Henrik H. Hansen   +12 more
wiley   +1 more source

Galectin-3 Inhibition in COVID-19

American Journal of Respiratory and Critical Care Medicine, 2023
Kiran Reddy, Alistair Nichol, Daniel F. McAuley   +2 more
openaire   +4 more sources

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

British Journal of Pharmacology, Volume 183, Issue 7, Page 1502-1516, April 2026.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy, Tamás Radovits, Tímea Bálint, Zoltán Horváth, Petra Kocsis‐Balogh, Ákos Gergely Tóth, Attila Oláh, Alex Ali Sayour, Bálint András Barta, Béla Merkely, Mihály Ruppert   +10 more
wiley   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source