Results 161 to 170 of about 18,236,146 (293)

Galectin-3 [PDF]

open access: yesScience-Business eXchange, 2010
openaire   +1 more source

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote ...
Udit Thakur, Jonathan M. Kalman
wiley   +1 more source

Galectin-3-A Multifunctional Molecule and a Key Player in Health and Disease. [PDF]

open access: yesMolecules
Lupu Surlea A   +7 more
europepmc   +1 more source

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

open access: yes
Background: Galectin-3 is a 32 kDa protein secreted by macrophages involved in processes such as cell activation, chemotaxis and phagocytosis. Galectin-3 has previously been shown to improve the ability of airway macrophages to ingest apoptotic cells ...
Melanie Erriah (6173654)   +7 more
core  

Glycoprotein-induced phase separation drives unconventional secretion of galectin-3. [PDF]

open access: yesNat Commun
Zhao Z   +16 more
europepmc   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng   +3 more
wiley   +1 more source

Galectin-3 and Coronary Artery Disease: An Inflammation-Based Approach. [PDF]

open access: yesJ Clin Med
Bora R   +6 more
europepmc   +1 more source

Role of Galectin-3 in T cell activation and apoptosis

open access: yes, 2007
Galectin-3,為分子量31 kDa的蛋白質,是屬於beta-galectose-binding lectin家族的一員,能正向與負向地調節T細胞和巨噬細胞的免疫功能。Galectin-3主要分布於細胞質內,然而近期研究也在細胞核、細胞表面以及細胞外間質偵測到Galectin-3的表現,暗示此分子為多功能性蛋白質。目前有越來越多的研究證據指出Galectin-3會參與調節T細胞免疫功能和細胞凋亡。Galectin-3能正向和負向地調節T細胞反應,但是Galectin ...
劉麗君, Liu, Li-Chun
core  

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

open access: yesImmunology, Volume 179, Issue 2, Page 269-286, October 2026.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu   +8 more
wiley   +1 more source

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