Results 41 to 50 of about 18,236,146 (293)
The two endocytic pathways mediated by the carbohydrate recognition domain and regulated by the collagen-like domain of galectin-3 in vascular endothelial cells. [PDF]
PLoS ONE, 2012 Galectin-3 plays an important role in endothelial morphogenesis and angiogenesis. We investigated the endocytosis of galectin-3 in human vascular endothelial cells and showed that galectin-3 could associate with and internalized into the cells in a ...
Xiaoge Gao +7 more
doaj +1 more source
PLoS ONE, 2011 BackgroundGalectin-3 is known to regulate cancer metastasis. However, the underlying mechanism has not been defined. Through the DNA microarray studies after galectin-3 silencing, we demonstrated here that galectin-3 plays a key role in up-regulating the
Seok-Jun Kim +6 more
doaj +1 more source
Frontiers in Oncology, 2022 IntroductionTo investigate the role of tumor galectin-1 and galectin-3 in patients with lung adenocarcinoma after definitive radiation therapy.MethodsA total of 41 patients with localized lung adenocarcinoma undergoing thoracic radiation therapy without ...
Chun-Chieh Huang +11 more
doaj +1 more source
Galectin-3 and cancer stemness [PDF]
Glycobiology, 2018 Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor progression and metastasis such as cell proliferation, homotypic/heterotypic aggregation, dynamic cellular transformation, migration and invasion,
Pratima, Nangia-Makker +2 more
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Galectin‐3 Is a Potential Mediator for Atherosclerosis [PDF]
Journal of Immunology Research, 2020 Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the pathological basis of many cardiovascular diseases such as coronary heart disease, heart failure, and stroke. Numerous studies have implicated inflammation as a key player in the initiation and progression of atherosclerosis. Galectin‐3 (Gal‐3) is
Ziyu Gao +5 more
openaire +3 more sources
Galectin-1 and galectin-3 as modulators of systemic CD4+ T-lymphocyte balance in colorectal cancer
Бюллетень сибирской медициныAim. To evaluate the relationships between plasma levels of galectin-1 and galectin-3 and the composition of CD4+ T-lymphocyte subpopulations (Th1, Th17, and Treg) in patients with colorectal cancer (CRC) and to determine a direct in vitro modulatory ...
V. S. Poletika +4 more
doaj +1 more source
Biomarker Insights, 2018 Introduction: Increased galectin-3 is associated with ischemic cardiomyopathy, although its role in early remodeling post-myocardial infarction (MI) has not been fully elucidated.
Wassim Mosleh +14 more
doaj +1 more source
Galectin-3 suppresses mucosal inflammation and reduces disease severity in experimental colitis
, 2017 Galectin-3, a member of the beta-galactoside-binding lectin family, expresses in many different immune cells and modulates broad biological functions including cell adhesion, cell activation, cell growth, apoptosis, and inflammation. However, the role of
許秉寧 +1 more
core +1 more source
Galectin-3 in angiogenesis and metastasis [PDF]
Glycobiology, 2014 Galectin-3 is a member of the family of β-galactoside-binding lectins characterized by evolutionarily conserved sequences defined by structural similarities in their carbohydrate-recognition domains. Galectin-3 is a unique, chimeric protein consisting of three distinct structural motifs: (i) a short NH2 terminal domain containing a serine ...
Tatsuyoshi, Funasaka +2 more
openaire +2 more sources
Galectin-3 plasma levels are associated with left atrial contractile function in long-distance runners. [PDF]
Exp PhysiolAbstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Contreras-Briceño F +6 more
europepmc +2 more sources