Results 161 to 170 of about 27,415 (188)
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Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork
Experimental Eye Research, 2003Galectins are a family of carbohydrate binding proteins involved in a variety of biological processes including cell-cell and cell-matrix interactions. We examined galectin-1 and galectin-3 to determine if galectins are expressed in the human trabecular meshwork and Schlemm's canal.Human trabecular meshworks were dissected from donor eyes within 12 hr ...
Michael P, Fautsch +2 more
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Galectin 3‐binding protein is a potential contaminant of recombinantly produced factor IX
Haemophilia, 2007Summary. Haemophilia B, or factor IX (FIX) deficiency, represents 15% of the hereditary haemophilias. The serious morbidity from the transmission of infectious agents in plasma‐derived material has mandated a need for the production of recombinant product.
M, Blostein, J, Cuerquis, J, Galipeau
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Galectin-3 Binding Protein Contaminates the Purification of Recombinant Factor IX.
Blood, 2006Abstract The hemophilas are the most common severe hereditary bleeding disorders. The standard treatment of these disorders is to infuse plasma concentrates of the missing coagulation factor. However, the high cost of replacement therapy and the serious morbidity from the transmission of infectious agents have mandated a need for ...
Jacques Galipeau +2 more
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Expression and function of galectin-3, a β-galactoside-binding protein in activated T lymphocytes
Journal of Leukocyte Biology, 2001AbstractA soluble beta-galactoside-binding lectin, galectin-3 has been shown tobe involved in cell adhesion and activation of immune cells. Althoughgalectin-3 is known to be expressed in various types of cells, it hasnot been shown whether galectin-3 is expressed in T lymphocytes.
H G, Joo +5 more
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Journal of Cellular Physiology, 1996
Galectin-3 is a Mr 30,000 protein with carbohydrate-binding specificity for type I and II ABH blood group epitopes and polylactosamine glycans expressed on cell surface and extracellular matrix glycoproteins such as laminin. Cell lines propagated from human normal mammary epithelia and from benign or infiltrating components of primary breast tumours ...
N, Le Marer, R C, Hughes
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Galectin-3 is a Mr 30,000 protein with carbohydrate-binding specificity for type I and II ABH blood group epitopes and polylactosamine glycans expressed on cell surface and extracellular matrix glycoproteins such as laminin. Cell lines propagated from human normal mammary epithelia and from benign or infiltrating components of primary breast tumours ...
N, Le Marer, R C, Hughes
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Clinical and experimental rheumatology, 2008
To determine the serum levels of galectin-3 (Gal-3) and galectin-3 binding protein (G3BP) and to evaluate the associations between clinical features and these levels in patients with Behçet's disease (BD).Fifty patients with BD (mean age 40.6 +/- SEM 1.4 years; 21 males, 29 females; 26 active and 24 inactive patients), 20 patients with rheumatoid ...
Y J, Lee +7 more
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To determine the serum levels of galectin-3 (Gal-3) and galectin-3 binding protein (G3BP) and to evaluate the associations between clinical features and these levels in patients with Behçet's disease (BD).Fifty patients with BD (mean age 40.6 +/- SEM 1.4 years; 21 males, 29 females; 26 active and 24 inactive patients), 20 patients with rheumatoid ...
Y J, Lee +7 more
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The Journal of Pathology, 1996
Galectin 3 is endogenous mammalian carbohydrate-binding protein with affinity for terminal beta-galactose residues, polylactosamine glycans, and ABH-blood group carbohydrate epitopes. To determine the distribution and regulation of galectin 3 during pulmonary injury, which is known to be accompanied by profound changes in the carbohydrate moieties of ...
M, Kasper, R C, Hughes
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Galectin 3 is endogenous mammalian carbohydrate-binding protein with affinity for terminal beta-galactose residues, polylactosamine glycans, and ABH-blood group carbohydrate epitopes. To determine the distribution and regulation of galectin 3 during pulmonary injury, which is known to be accompanied by profound changes in the carbohydrate moieties of ...
M, Kasper, R C, Hughes
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Plasma galectin-3-binding protein level in patients with systemic lupus erythematosus
Tanta Medical Journal, 2018Background Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects multiple organs. It is characterized by production of autoantibodies and immune complex deposition in various organs, leading to inflammation and tissue destruction. Although the definite etiopathogenesis of SLE remains unclear, many different mechanisms may contribute
SamahElsayed Abo-Elyazeed +3 more
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Galectin-3 Binding Protein and Galectin-3: Novel Factors Promoting Venous Thrombosis
Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2013J A, Diaz +7 more
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[Cancer-associated carbohydrate-binding protein galectin-3 and its therapeutic ligands].
Sheng li ke xue jin zhan [Progress in physiology], 2012Carbohydrates are proved to be involved in recognition processes, including adhesion between cells, adhesion of cells to the extracellular matrix, and specific recognition of cells by one another. Galectin-3 is a nonenzymatic carbohydrate-binding protein present in mammals, whose conserved carbohydrate-recognition domain preferentially binds to ...
Hui, Bai +4 more
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