Results 161 to 170 of about 70,530 (251)

Galectin-8 [PDF]

Journal of Biological Chemistry, 1995
Yaron R. Hadari, Keren Paz, Roi Dekel, Tomislav Mestrovic, Domenico Accili, Yehiel Zick   +5 more
openaire   +1 more source

Fluorophore Modulates Intracellular Distribution of Enzyme‐Instructed Self‐Assembly of Short Peptides in Osteosarcoma Cells

Small Methods, Volume 10, Issue 3, 9 February 2026.
Fluorophores at the peptide C‐terminus reprogram EISA behavior in osteosarcoma cellsshifting ER vs mitochondrial targeting, altering assembly, and tuning cytotoxicity. Abstract Enzyme‐instructed self‐assembly (EISA) of peptides offers a versatile strategy for developing intracellular nanomedicines, yet the role of C‐terminus fluorophores in modulating ...
Yali Huang, Meihui Yi, Yuchen Qiao, Bing Xu   +3 more
wiley   +1 more source

Exploring the Potential Causal Relationship of Galectin Levels and Gynecologic Cancers: A Two-Sample Mendelian Randomization Study. [PDF]

Int J Womens Health
Dong H, Nie S, Ni N, Guo L, Liu Q.
europepmc   +1 more source

Galectin-12

, 2012
Galectin-12, a member of the galectin family of animal lectins, is preferentially expressed in adipocytes. We recently reported that this galectin is localized on lipid droplets, specialized organelles for fat storage. Galectin-12 regulates lipid degradation (lipolysis) by modulating lipolytic protein kinase A (PKA) signaling.
Yang, Ri-Yao, Havel, Peter, Liu, Fu-Tong
openaire   +2 more sources

T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri, Negar Asadollahei, Yasamin Haghir‐Sharif‐Zamini, Homeyra Seydi, Mahsa Salehi, Mehrnaz Mesdaghi, Mustapha Najimi, Massoud Vosough   +7 more
wiley   +1 more source

Sirt6 deficiency in mast cells promotes adipose fibroinflammation in obesity through galectin-3 signaling. [PDF]

Nat Commun
Song MY, Jeon YG, Do Yang J, Moon YJ, Kim JB, Bae EJ, Park BH.   +6 more
europepmc   +1 more source

Exosomal HMGB1 Orchestrates NSCLC Progression and Immunosuppressive Macrophage Polarisation Through the TLR4/NF‐κB/IL‐6/STAT3 Signalling Cascade

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT High mobility group box 1 (HMGB1), a prototypical alarmin and chromatin‐binding protein, has emerged as a critical mediator of tumour‐associated inflammation and immune regulation. Although its soluble form has been implicated in various malignancies, the functional contribution of HMGB1 encapsulated within exosomes remains incompletely ...
Jia‐Ru Huang, Wen‐Chao Gu, Ya‐Ping Yuan, Jun‐Xia Yang, Yan Chen, Xiao‐Xia Guo, Wei Ding   +6 more
wiley   +1 more source

From Metabolic Syndrome to Atrial Fibrillation: Linking Inflammatory and Fibrotic Biomarkers with Atrial Remodeling and Imaging-Based Evaluation-A Narrative Review. [PDF]

Metabolites
Merce AG, Nisulescu DD, Hermenean A, Burciu OM, Munteanu IR, Merce AP, Brie DM, Mornos C.   +7 more
europepmc   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 310-320, February 2026.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source

Galectin-7 as a biomarker for aggressiveness and poor prognosis in thymic epithelial tumors. [PDF]

Transl Oncol
Lv Y, Gu Z, Li K, Mao T, Zhang X, Xu N, Fang W, Sun Q.   +7 more
europepmc   +1 more source