Results 11 to 20 of about 70,530 (251)
Annals of translational medicine, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
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Current Biology, 2022 Banfer and Jacob introduce us to galectins - β-galactoside-binding lectins - and their range of functions in multicellular organisms.
Sebastian, Bänfer, Ralf, Jacob
+7 more sources
Galectinology of Equine Pregnancy
Animals, 2022 Galectins are a family of proteins that bind to glycans, acting in a cytokine-like manner throughout the body. In the majority of mammalians, galectins have been found to be involved in pregnancy maintenance, but few studies have evaluated this in the ...
Carleigh E. Fedorka +2 more
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Galectins can serve as biomarkers in COVID-19: A comprehensive systematic review and meta-analysis
Frontiers in Immunology, 2023 BackgroundGalectins are an eleven-member class of lectins in humans that function as immune response mediators and aberrancies in their expression are commonly associated with immunological diseases.
Amir Hossein Behnoush +7 more
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“Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective
Cells, 2020 Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein aggregates or chemicals, which can provoke membrane damage at the plasma membrane or within the endo-lysosomal compartments.
Coralie F. Daussy, Harald Wodrich
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FEBS Open Bio, 2022 We previously observed that genomic loss of galectin‐3 (Gal‐3; encoded by Lgals3) in mice has a significant protective effect on age‐related bone loss.
Kevin A. Maupin +5 more
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Atg8ylation as a general membrane stress and remodeling response
Cell Stress, 2021 The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
doaj +1 more source
Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function
Frontiers in Immunology, 2020 The tumor microenvironment (TME) is composed of multiple infiltrating host cells (e.g., endothelial cells, fibroblasts, lymphocytes, and myeloid cells), extracellular matrix, and various secreted or cell membrane-presented molecules.
Gustavo Rodrigues Rossi +2 more
doaj +1 more source
Brain Pathology, 2009 AbstractMalignant gliomas, especially glioblastomas, are associated with a dismal prognosis. Despite advances in diagnosis and treatment, glioblastoma patients still have a median survival expectancy of only 14 months. This poor prognosis can be at least partly explained by the fact that glioma cells diffusely infiltrate the brain parenchyma and ...
Le Mercier, Marie +4 more
openaire +2 more sources
Plasma Galectin-9 Concentrations in Normal and Diseased Condition
Cellular Physiology and Biochemistry, 2018 Background/Aims: Galectin-9 is a soluble immune modulator with versatile functions, including a role as an immune checkpoint molecule. Therefore, the amount of galectin-9 in the blood may reflect an individual’s immunological balance.
Toshiro Niki +6 more
doaj +1 more source