Results 121 to 130 of about 18,236,139 (292)
Evaluation of Galectin-3 in Graves’ Disease With and Without Ophthalmopathy
Endocrinology Research and Practice, 2023 Objective: There is a link between thyroid-associated ophthalmopathy and Graves’ disease; however, the exact pathophysiological mechanism remains unclear.
Muhammed Akın +4 more
doaj
Pest Management Science, EarlyView.Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa +16 more
wiley +1 more source
Galectin-3: clinical utility and prognostic value in patients with heart failure
, 2013 Frank KramerClinical Sciences, Global Biomarker Strategy and Development, Bayer HealthCare, Wuppertal, GermanyAbstract: This review summarizes the key findings of 14 clinical trials in which Galectin-3 was assessed as a biomarker of heart failure.
Kramer, Frank, Kramer F
core +1 more source
Phytotherapy Research, EarlyView.Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo +3 more
wiley +1 more source
Integrative Zoology, EarlyView.High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Galectin-3 as a Potential Target to Prevent Cancer Metastasis
, 2015 Interactions between two cells or between cell and extracellular matrix mediated by protein–carbohydrate interactions play pivotal roles in modulating various biological processes such as growth regulation, immune function, cancer metastasis, and ...
Dina M. M. AlSadek, Hafiz Ahmed
core +1 more source
, 2019 Introduction: The discoveries that sugars are a highly versatile platform to generate biochemical messages and that glycan-specific receptors (lectins) are a link between these signals and their bioactivity explain the interest in endogenous lectins such
Antonio Romero (348813) +1 more
core +1 more source
Galectin-3 and phagocyte function in asthma
Asthma is a chronic obstructive airway condition that is thought to affect 300 million people globally including around 2.5 million Australians. Asthma-related expenditure in Australia alone is estimated to be over $600 million dollars annually, half of ...
Melanie Erriah (6173654)
core
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
Allergy, EarlyView.This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source
Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma
Allergy, EarlyView.This study investigates the effect of mepolizumab on the proteomic and transcriptomic profile of blood eosinophils in SEA patients. Mepolizumab reduces the migratory capacity and effector‐related molecular signatures of circulating eosinophils in SEA patients.
Pablo Miguéns‐Suárez +14 more
wiley +1 more source