Results 121 to 130 of about 18,892,704 (362)

Galectin‐3 and risk of atrial fibrillation: A systematic review and meta‐analysis

Journal of clinical laboratory analysis (Print), 2020
Galectin‐3 is an inflammatory marker that is raised in myocardial fibrosis and inflammation. Recent studies have explored its role in predicting atrial fibrillation (AF) outcomes.
M. Gong, A. Cheung, Qunshan Wang, Guangping Li, C. Goudis, G. Bazoukis, G. Lip, A. Baranchuk, P. Korantzopoulos, K. Letsas, G. Tse, Tong Liu   +11 more
semanticscholar   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Elevated galectin-3 levels detected in women with hyperglycemia during early and mid-pregnancy antagonizes high glucose − induced trophoblast cells apoptosis via galectin-3/foxc1 pathway

Molecular Medicine, 2023
Objective This study was to evaluate plasma galectin-3 levels from early pregnancy to delivery and explore the effects of galectin-3 on the function of trophoblast cells under high glucose exposure. Methods The plasma galectin-3 levels were quantified by
Yu Deng, Hongyan Jin, Jie Ning, Dong Cui, Muqiu Zhang, Huixia Yang   +5 more
doaj   +1 more source

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]

, 2018
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro, García Domínguez, Irene, García Revilla, Juan, Martínez de Pablos, Rocío, Roca Ceballos, María Angustias, Santiago Pavón, Martiniano, Venero Recio, José Luis, Veselá, Karolina   +7 more
core   +3 more sources

Supplementary Table 1 from Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin [PDF]

, 2023
Russell R. Braeuer, Maya Zigler, Takafumi Kamiya, Andrey S. Dobroff, Li Huang, Woonyoung Choi, David J. McConkey, Einav Shoshan, Aaron K. Mobley, Renduo Song, Avraham Raz, Menashe Bar‐Eli   +11 more
openalex   +1 more source

An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.

Cancer Research, 2019
A combination therapy approach is required to improve tumor immune infiltration and patient response to immune checkpoint inhibitors that target negative regulatory receptors.
Lynda Vuong, E. Kouverianou, C. Rooney, B. McHugh, S. Howie, C. Gregory, S. Forbes, N. Henderson, F. Zetterberg, U. Nilsson, H. Leffler, P. Ford, A. Pedersen, L. Gravelle, Susan Tantawi, H. Schambye, T. Sethi, A. MacKinnon   +17 more
semanticscholar   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE

Кардиоваскулярная терапия и профилактика, 2017
Aim. To assess the level of galectin-3 in blood serum of metabolic syndrome patients (MS), with heart failure (CHF).Material and methods. Totally, 43 patients investigated, with MS, and of those 37 CHF patients and 33 on-CHF, of those 17 had CHF ...
O. M. Drapkina, R. N. Shepel, T. A. Deeva   +2 more
doaj   +1 more source

Serum apelin and galectin-3 in preeclampsia in Iraq

Hypertension in Pregnancy, 2020
Objective This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE).
Aamal Sattar Taha, Zohreh Zahraei, Hussein Kadhem Al-Hakeim   +2 more
doaj   +1 more source

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins [PDF]

, 2011
Thioglycosides offer the advantage over O-glycosides to be resistant to hydrolysis. Based on initial evidence of this recognition ability for glycosyldisulfides by screening dynamic combinatorial libraries, we have now systematically studied ...
Aguilera, Ahmad, Alonso-Plaza, André, André, André, André, André, André, André, André, Bachhawat-Sikdar, Barkley, Bayly, Beatriz de Pascual-Teresa, Beer, Bharadwaj, Bianchet, Borrok, Caraballo, Czifrák, Darden, Davis, De Waard, Dolores Solís, Eliza Buzamet, F. Javier Cañada, Fernandez-Alonso, Gabius, Gabius, Gabius, Gabius, Gabius, Gabius, Galanina, Gilleron, Gloria Fernández-Cureses, Gupta, Hans-Joachim Gabius, Hartley, Hilaire, Hotchkiss, Jesús Jiménez-Barbero, Jiménez, Jiménez, Jiménez, Jiménez-Barbero, João P. Ribeiro, Karla Ramírez-Gualito, Kiefel, Kolympadi, Kopitz, Krzeminski, Kübler, Langbein, Lee, Lee, Leyden, López-Lucendo, Margarita Menéndez, Maria Morando, Morris, Muñoz, Olof Ramström, Pei, Ramkumar, Ramström, Ramström, Ribeiro, Ribeiro, Rivera-Sagredo, Roda, Rorive, Rémi Caraballo, Sabine André, Sanchez-Ruderisch, Schmidt, Schwarz, Schweizer, Siebert, Solís, Solís, Sonsoles Martín-Santamaría, Sparrow, Stannard, Stirpe, Strino, Strino, Szilágyi, Szilágyi, Villalobo, Wu   +91 more
core   +2 more sources