Results 221 to 230 of about 18,892,704 (362)

Arrhythmogenic cardiomyopathy related phenotypes are detected and pharmacologically modulated in Galectin-3 zebrafish models [PDF]

open access: bronze
Giovanni Risato   +13 more
openalex   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan   +7 more
wiley   +1 more source

Evaluation of galectin-3 expression in non-neoplastic and neoplastic lesions of thyroid

open access: diamond, 2021
Dept.of Pathology, HMCH Bhubaneswar, Odisha, India   +1 more
openalex   +1 more source

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy [PDF]

open access: gold, 2021
Ri‐Yao Yang   +16 more
openalex   +1 more source

Focus on Molecules: Galectin-3 [PDF]

open access: yesExperimental Eye Research, 2011
Pablo, Argüeso, Noorjahan, Panjwani
openaire   +2 more sources

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri   +11 more
wiley   +1 more source

Galectin-3 Inhibition in COVID-19

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2023
Kiran Reddy   +2 more
openaire   +4 more sources

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 3, Page 696-710, May 2026.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan   +9 more
wiley   +1 more source

Prognostic Values of Galectin-3 and the Macrophage Migration Inhibitory Factor (MIF) in Human Colorectal Cancers [PDF]

open access: bronze, 2003
H Legendre   +8 more
openalex   +1 more source

Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation

open access: yesGlia, Volume 74, Issue 5, May 2026.
– CSF2, IL3, and TNFɑ directly promote microglial proliferation. – Neuron‐secreted factors suppress microglial proliferation. – IL1 cytokines promote CSF2 release from astrocytes, which promotes microglial proliferation. ABSTRACT Microglia—the predominant immune cell of the central nervous system (CNS)—possess an astounding capacity for proliferation ...
Brady P. Hammond   +4 more
wiley   +1 more source

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