Galectin-3 promotes FBXL5-dependent ubiquitination and degradation of YAP1 to constrain colorectal cancer growth. [PDF]
Zeng X +5 more
europepmc +1 more source
γ-Tocotrienol inhibition of galectin-3 expression, distribution and oligomerization in highly metastatic breast cancer cells. [PDF]
Grazier JJ, Sylvester PW.
europepmc +1 more source
Galectin-3 Binds to the Allosteric Site and Activates Integrins αvβ3, αIIbβ3, and α5β1, and Lactose Inhibits This Activation. [PDF]
Takada YK, Wan YY, Takada Y.
europepmc +1 more source
A novel circulating osteoimmunological signature for diagnosis: integrating CXCL2, FYN, galectin-3, and STING in postmenopausal osteoporosis. [PDF]
Ma S, Yao Q, Bao X, Li Y.
europepmc +1 more source
Expression and Significance of Galectin-3 and Galectin-3 Binding Proteins in Preeclampsia
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Galectin-3, a 31 kDa member of the beta-galactoside-binding proteins, is an intracellular and extracellular lectin which interacts with intracellular glycoproteins, cell surface molecules and extracellular matrix proteins. Galectin-3 is expressed widely in epithelial and immune cells and its expression is correlated with cancer aggressiveness and ...
Yukinori Takenaka +2 more
exaly +3 more sources
The regulation of inflammation by galectin‐3
Immunological Reviews, 2009Summary: Galectin‐3 is a β‐galactoside‐binding animal lectin of appro‐ ximately 30 kDa and is evolutionarily highly conserved. Galectin‐3 is promiscuous, its localization within the tissue micro‐environment may be extracellular, cytoplasmic, or nuclear, and it has a concentration‐dependent ability to be monomeric or form oligomers.
Neil Henderson
exaly +4 more sources
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migration, invasion and metastasis. In this review, the associations of the expression and localization of Gal-
Lin, Song +5 more
openaire +2 more sources
The expression profiles of the galectin gene family in primary and metastatic papillary thyroid carcinoma with particular emphasis on galectin-1 and galectin-3 expression [PDF]
Introduction Galectin family members have been demonstrated to be abnormally expressed in cancer at the protein and mRNA level. This study investigated the levels of galectin proteins and mRNA expression in a large cohort of patients with papillary ...
Vinod Gopalan +2 more
exaly +2 more sources

