Results 261 to 270 of about 18,236,139 (292)

Galectin-3

Cardiovascular Drugs and Therapy, 2014
Myocardial galectin-3 is upregulated upon cardiac stressors such as angiotensin II and pressure overload leading to cardiac remodeling and heart failure. The expression level of galectin-3 mirrors the progression and severity of heart failure and therefore, galectin-3 is being used as a biomarker for heart failure.
de Boer, Rudolf A., van der Velde, A. Rogier, Mueller, Christian, van Veldhuisen, Dirk J., Anker, Stefan D., Peacock, W. Frank, Adams, Kirkwood F., Maisel, Alan   +7 more
openaire   +1 more source

Galectin-1 and galectin-3 in the trophoblast of the gestational trophoblastic disease

Placenta, 2004
While the presence and distribution of galectin-1 and galectin-3 in different normal trophoblast cell populations is known, no information is available regarding their occurrence in malignant trophoblast of gestational trophoblastic disease (GTD). Galectins-1 and -3 have, however, been implicated in malignancies of other tissues.
M, Bozić, M, Petronijević, S, Milenković, J, Atanacković, J, Lazić, Lj, Vićovac   +5 more
openaire   +2 more sources

Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinoma

Human Pathology, 2001
Galectins, a family of beta-galactoside-binding animal lectins, might be involved in tumor progression. In this study, the expression patterns of galectin-1 and -3 were examined immunohistochemically in intrahepatic cholangiocarcinoma (ICC), with emphasis on its development and progression as well as its histopathologic features, by use of samples of ...
T, Shimonishi, K, Miyazaki, N, Kono, H, Sabit, K, Tuneyama, K, Harada, J, Hirabayashi, K, Kasai, Y, Nakanuma   +8 more
openaire   +2 more sources

Understanding the biochemical activities of galectin-1 and galectin-3 in the nucleus

Glycoconjugate Journal, 2002
Nuclear extracts (NE), capable of carrying out splicing of pre-mRNA, contain galectin-1 and galectin-3. NE depleted of galectins-1 and -3 concomitantly lose their splicing activity. The activity of the galectin-depleted extract can be reconstituted by the addition of either galectin-1 or galectin-3.
Ronald J, Patterson, Weizhong, Wang, John L, Wang   +2 more
openaire   +2 more sources

Galectin-3 as a cardiac biomarker

Clinica Chimica Acta
Galactoside-derived lectin galectin-3 (Gal-3) is an effective and promising cardiac fibrosis marker that can be used in heart failure management. Nevertheless, its clinical use demands strict standardization of preanalytical, analytical, and reporting methods.
Asif Ahmad, Bhat, Yahia, Alghazwani, Kumarappan, Chidambaram, M M, Rekha, Samir, Sahoo, Pavan, Goud, Nadeem, Sayyed, Vikas, Jakhmola, Moyad, Shahwan, Imran, Kazmi, Sami I, Alzarea, Omar Awad, Alsaidan   +11 more
openaire   +2 more sources

An updated patent review of galectin-1 and galectin-3 inhibitors and their potential therapeutic applications (2016–present)

Expert Opinion on Therapeutic Patents, 2021
Swetha Sanam, Aaftaab Sethi, Mallika Alvala   +2 more
exaly  

GALECTIN-3 INHIBITORS

2021
LIU CHUNJIAN, WANG WEI, ELLSWORTH BRUCE A, BALOG JAMES AARON, REGUEIRO-REN ALICIA   +4 more
openaire   +2 more sources

Galectin 3

1997
A. Neil Barclay, Marion H. Brown, S.K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe   +5 more
openaire   +1 more source

Galectin 3

2000
Clare M. Isacke, Michael A. Horton
openaire   +1 more source

Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot

Reviews in Endocrine and Metabolic Disorders, 2022
Chunlan Zhang, Tian Li, Yang Xiao
exaly