Results 81 to 90 of about 18,236,139 (292)

Persistent IL‐18 fuels expansion of CD38+HLA‐DR+CD8+ T cells in Still's disease and macrophage activation syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL‐18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further IL‐18 ...
Greta Rogani   +17 more
wiley   +1 more source

The role of Galectin-3 in promoting metastasis of papillary thyroid carcinoma

open access: yesZhongguo aizheng zazhi, 2017
Background and purpose: Papillary thyroid cancer (PTC) is one of the most common carcinomas in humans. Galectin-3 is a multifunctional protein which regulates different process of tumorigenesis.
陆伟辉, 王 聪, 李 宸
doaj  

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE

open access: yesКардиоваскулярная терапия и профилактика, 2017
Aim. To assess the level of galectin-3 in blood serum of metabolic syndrome patients (MS), with heart failure (CHF).Material and methods. Totally, 43 patients investigated, with MS, and of those 37 CHF patients and 33 on-CHF, of those 17 had CHF ...
O. M. Drapkina   +2 more
doaj   +1 more source

Galectin-3 in diabetic patients

open access: yesClinical Chemistry and Laboratory Medicine (CCLM), 2014
Galectin-3 is a versatile molecule which exerts several and sometimes opposite functions in various pathophysiological processes. Recently, galectin-3 has gained attention as a powerful predictor of heart failure and mortality, thus becoming a useful prognostic marker in clinical practice.
PUGLIESE, Giuseppe   +4 more
openaire   +4 more sources

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

Periodontal diseases and adverse pregnancy outcomes. Present and future

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis   +3 more
wiley   +1 more source

Macrophage‐derived galectin‐3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF‐κB/NLRP3 during atherosclerosis

open access: yesClinical and Translational Medicine
Background Pyroptosis, apoptosis and necroptosis (PANoptosis) simultaneously occur and are extensively cross‐linked in infectious and inflammatory diseases.
Zihui Yuan   +5 more
doaj   +1 more source

Data_Sheet_1_The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer.docx

open access: yes, 2019
Human cancer cells operate a variety of effective molecular and signaling mechanisms which allow them to escape host immune surveillance and thus progress the disease.
Svetlana S. Sakhnevych (6559877)   +18 more
core   +1 more source

Animal lectins as cell adhesion molecules [PDF]

open access: yes, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

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