Results 61 to 70 of about 18,892,704 (362)
Frontiers in Oncology, 2022 IntroductionTo investigate the role of tumor galectin-1 and galectin-3 in patients with lung adenocarcinoma after definitive radiation therapy.MethodsA total of 41 patients with localized lung adenocarcinoma undergoing thoracic radiation therapy without ...
Chun-Chieh Huang +11 more
doaj +1 more source
Human T cell glycosylation and implications on immune therapy for cancer [PDF]
, 2020 Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico +3 more
core +1 more source
Frontiers in Immunology, 2020 COVID-19 disease have become so far the most important sanitary crisis in the XXI century. In light of the events, any clinical resource should be considered to alleviate this crisis.
J. García-Revilla +3 more
semanticscholar +1 more source
Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal.
Developmental Cell, 2019 Endomembrane damage elicits homeostatic responses including ESCRT-dependent membrane repair and autophagic removal of damaged organelles. Previous studies have suggested that these systems may act separately.
Jingyue Jia +14 more
semanticscholar +1 more source
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
European Respiratory Journal, 2020 Galectin (Gal)-3 is a profibrotic β-galactoside-binding lectin that plays a key role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) and IPF exacerbations. TD139 is a novel and potent small-molecule inhibitor of Gal-3.
N. Hirani +24 more
semanticscholar +1 more source
, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core +1 more source
Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3
Nature Communications, 2020 Liquid-liquid phase separation (LLPS) explains many intracellular activities, but its role in extracellular functions has not been studied to the same extent.
Y. Chiu +6 more
semanticscholar +1 more source
Galectin-3 and cancer stemness [PDF]
Glycobiology, 2018 Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor progression and metastasis such as cell proliferation, homotypic/heterotypic aggregation, dynamic cellular transformation, migration and invasion,
Pratima, Nangia-Makker +2 more
openaire +2 more sources
Biomarker Insights, 2018 Introduction: Increased galectin-3 is associated with ischemic cardiomyopathy, although its role in early remodeling post-myocardial infarction (MI) has not been fully elucidated.
Wassim Mosleh +14 more
doaj +1 more source
Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]
, 2005 Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines +5 more
core +1 more source