Results 111 to 120 of about 9,659 (276)
Expression and functional characterization of galectins in human colorectal cancer [PDF]
, 2010 Galectins are a family of proteins defined by shared consensus amino acid sequence and affinity for β-galactose-containing oligosaccharides. These proteins have been associated with various biological processes, such as cell adhesion, proliferation ...
Satelli, Arun
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Bangladesh Journal of Pharmacology, 2014 Galectins are a family of structurally related carbohydrate-binding proteins and some galectins play a major role in initiation, progression and dissemination of different types of tumors.
Vipperla Bhavaniprasad +2 more
doaj +2 more sources
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
iNew Medicine, EarlyView.ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Molecules, 2017 Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite their highly conserved carbohydrate binding motifs with essentially identical structures, their affinities for lactose, a common galectin inhibitor, vary
Chih-Ta Henry Chien +3 more
doaj +1 more source
Extracellular galectins as controllers of cytokines in hematological cancer
, 2018 Galectins and cytokines are both secreted proteins whose levels are prognosis factors for several cancers. Extracellular galectins bind to the glycans decorating glycoproteins and are overproduced in most cancers.
Pierre van der Bruggen +5 more
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Journal of Surgical Oncology, EarlyView.ABSTRACT Liver transplantation (LT) is the definitive treatment for early hepatocellular carcinoma (HCC), based on established criteria. Pre‐transplant imaging occasionally underestimates the tumor burden or biological aggressiveness, leading to explant pathology that exceeds the projection criteria, such as Milan.
Serkan Sucu +2 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis
Cell Communication and SignalingFibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an intracellular signaling.
Dominika Żukowska +7 more
doaj +1 more source
Galectins: An Amazing Marker and a Potential Therapeutic Target [PDF]
Galectins (Gal) are a wide group of proteins expressed in various cells, and they are particularly known for their ability to recognize and bind carbohydrates. We present current evidence showing that Gal play roles in both acute and chronic inflammation
Gaukhar Bakhtiyarova, Mehtap Tınazlı
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