Results 211 to 220 of about 13,626 (296)

Organoruthenium Glycomimetics Exhibit High Selectivity and Nanomolar Affinity for Human Galectin-1. [PDF]

J Med Chem
Hamala V, Kurfiřt M, Červenková Št́astná L, Dvořák F, Bernášková J, Sýkorová A, Kozák J, Zavřel M, Staroňová T, Šebest P, Ostatná V, Červený J, Bojarová P, Holčáková J, Hrstka T, Hrstka R, Karban J.   +16 more
europepmc   +1 more source

Single‐Cell Profiling Reveals RAB13+ Endothelial Cells and Profibrotic Mesenchymal Cells in Aged Human Bone Marrow

Aging Cell, Volume 25, Issue 4, April 2026.
Integrated single‐cell, spatial transcriptomic, and immunofluorescence analyses reveal profound aging‐associated remodeling of the non‐immune human bone marrow niche. Aging is marked by endothelial dysfunction, emergence of RAB13+ arterial endothelial cells, and expansion of profibrotic THY1+ mesenchymal cells, identifying potential cellular targets ...
Itziar Cenzano, Miguel Cócera, Ana Rosa Lopez‐Perez, Lorea Campos‐Dopazo, Javier Ruiz, Ignacio Sancho, Patxi San Martin‐Uriz, Paula Aguirre‐Ruiz, Sarai Sarvide, Amaia Vilas‐Zornoza, Purificacion Ripalda‐Cemborain, Diego Alignani, Aitziber Lopez, Marta Miñana Barrios, Delia Quilez Agreda, Jin Ye, Robert Lehmann, Laura Sudupe, Marta Abengozar‐Muela, Álvaro Lopez‐Janeiro, Luis‐Esteban Tamariz‐Amador, Emma Muiños‐López, Borja Saez, Jesper Tegner, Isabel A. Calvo, David Gomez‐Cabrero, Felipe Prosper   +26 more
wiley   +1 more source

Tumor glyco-immunology, glyco-immune checkpoints and immunotherapy. [PDF]

J Immunother Cancer
Pinho SS, Macauley MS, Läubli H.
europepmc   +1 more source

Single‐Cell Profiling Reveals Distinct Immune Communication Networks in Centenarians and Elderly Controls

Aging Cell, Volume 25, Issue 4, April 2026.
Single‐cell profiling of PBMCs from centenarians, their offspring, and elderly controls revealed distinct myeloid‐to‐effector immune cell communication programs. General aging was characterized by SASP‐enriched signaling associated with immunosenescence, whereas healthy aging showed positive immune regulatory signaling associated with enhanced ...
Liwei Qiu, Chen Dong, Rui Zhao, Huiyuan Ye, Jian‐lin Gao, Yizhi Chen, Chi Sun, Zhifeng Gu   +7 more
wiley   +1 more source

ASGR2 and CLEC12A as Prognostically Relevant C-Type Lectin Hubs in Glioblastoma. [PDF]

Int J Mol Sci
Pace A, Alfano C, D'Angelo L, Napoletano C, Zizzari IG, Santoro A, Nuti M, Farina L, Petti M, Rughetti A.   +9 more
europepmc   +1 more source

Galectin-3 [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Peripheral Regulatory T Cells Display Dynamic Memory Subset Frequency and Inhibitory Marker Expression Across Pregnancy

American Journal of Reproductive Immunology, Volume 95, Issue 4, April 2026.
ABSTRACT Problem Pregnancy is characterized by significant changes in peripheral immunity. Total CD3+ T cells decrease across pregnancy while Forkhead Box P3+ T‐regulatory cells (FoxP3+Tregs) peak in mid‐pregnancy, the latter of which are key to healthy outcomes.
Nolawit Mulugeta, M. Quinn Peters, Cara Tobey, Jia Wong, Abigail L. P. Spray, Blair Armistead, Yonghou Jiang, Ronit Katz, Raj Shree, Lucia Vojtech, Whitney E. Harrington   +10 more
wiley   +1 more source

Exploring the Potential Causal Relationship of Galectin Levels and Gynecologic Cancers: A Two-Sample Mendelian Randomization Study. [PDF]

Int J Womens Health
Dong H, Nie S, Ni N, Guo L, Liu Q.
europepmc   +1 more source

Nintedanib Lacks Efficacy in a Spirometry‐Confirmed and Bleomycin‐Induced Mouse Model of Idiopathic Pulmonary Fibrosis

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Nintedanib, a multitargeted tyrosine kinase inhibitor, is approved for idiopathic pulmonary fibrosis (IPF) for its ability to slow lung function decline. This study systematically evaluated the effects of nintedanib across three independent treatment intervention studies in the single‐dose bleomycin (BLEO) mouse model of IPF.
Jamal Bousamaki, Grzegorz Maciag, Asbjørn Graver Petersen, Stefanie H. Korntner, Stine Marie Jansen, Susanne E. Pors, Linn Salto Mamsen, Silas A. Rasmussen, Casper Gravesen Salinas, Louise Humle Kruse, Michael Feigh, Ulf Simonsen, Henrik H. Hansen   +12 more
wiley   +1 more source