Results 201 to 210 of about 13,626 (296)

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

MedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun, Jiachen Qu, Sheng Peng, Yanan Hu, Amity Eliaz, Glenn M. Chertow, Isaac Eliaz, Zhiyong Peng   +7 more
wiley   +1 more source

A Narrative Review on the Multifaceted Roles of Galectins in Host-Pathogen Interactions During <i>Helicobacter pylori</i> Infection. [PDF]

Int J Mol Sci
Stojanovic B, Zdravkovic N, Petrovic M, Jovanovic I, Stojanovic BS, Dimitrijevic Stojanovic M, Nesic J, Paunovic M, Milivojcevic Bevc I, Mirkovic N, Pavlovic M, Zornic N, Milosevic B, Tasic-Uros D, Zivic J, Colakovic G, Cvetkovic A.   +16 more
europepmc   +1 more source

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

MedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge, Yue‐Hua Li, Xuan Yu, Ming‐Yan Xing, Yi‐Hui Gu, Wei Wang, Jing‐Xuan Huang, Jun Liu, Hai‐Bing Zhang, Cheng‐Jiang Wei, Zhi‐Chao Wang, Qing‐Feng Li   +11 more
wiley   +1 more source

Methanol Extract from <i>Ranunculus repens</i> L. Down-Regulated Galectins 4 and 9, and Mitigated Chronic Pancreatitis in an Experimental Rat Model. [PDF]

Antioxidants (Basel)
Khenchil A, Rechreche H, Abbes A, Pettineo E, Dianzani C, Bensam M, Sobhi W, Pizzimenti S.   +7 more
europepmc   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, Volume 15, Issue 4, April 2026.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Human Milk Oligosaccharides Multivalently Presented on Defined Synthetic Neo-Glycoproteins Are Nanomolar Ligands of Tandem-Repeat Galectins. [PDF]

Biomacromolecules
Červený J, Heine V, Hovorková M, Brož P, Filipová E, Kulik N, Hubálek M, Cvačka J, Petrásková L, Florencio-Zabaleta M, Delgado S, Pelantová H, Bosáková Z, Elling L, Jiménez-Barbero J, Ardá A, Křen V, Bojarová P.   +17 more
europepmc   +1 more source

Fibrosis‐Driven Surgical Risk After Thyroid Nodule Ablation: Quantitative Clinicopathological Determinants of Complications in Post‐Ablative Thyroidectomy—A Retrospective Cohort Study

World Journal of Surgery, Volume 50, Issue 4, Page 914-923, April 2026.
Thermal ablation is increasingly used for selected benign and low‐risk thyroid nodules, yet some patients still require thyroidectomy for regrowth, persistent symptoms, or new oncologic concern. The surgical and pathological impact of ablation‐induced remodeling remains incompletely defined.
Daqi Zhang, Alvino Boero, Giacomo Gazzano, Andrea Satta, Laura Fugazzola, Carla Colombo, Francesco Brucchi, Gianlorenzo Dionigi   +7 more
wiley   +1 more source

Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferation. [PDF]

Proc Natl Acad Sci U S A
Rodgers-Furones A, Brands T, van Gameren G, Florencio-Zabaleta M, Bathini M, Delgado S, Wijfjes Z, Fedorova K, Classens R, Kroese L, Verdoes M, van Mierlo G, Jiménez-Barbero J, Lindeboom RGH, Ardá A, van Spriel AB, Cano LQ.   +16 more
europepmc   +1 more source

Galectin‐9high Neutrophils Exacerbate Radiation‐Induced Frailty

Aging Cell, Volume 25, Issue 4, April 2026.
EccDNA shedding after skin radiation injury activates the JAK1/2‐STAT1 pathway in splenic GMP cells to induce the production of GAL‐9high neutrophils. This unique population of hyperactive GAL‐9high neutrophils is identified with characteristics of elevated NETs and IFN‐γ, etc.
Zhuo Cheng, Le Ma, Yan Chen, Jialun Li, Yali Dai, Wentao Xie, Yingjie Li, Tianlang Xu, Zhihe Hu, Weilin Huang, Jingyuan Zhou, Jie Wu, Long Chen, Chunmeng Shi   +13 more
wiley   +1 more source

Galectin 3 [PDF]

, 2020
openaire   +2 more sources