Results 181 to 190 of about 13,626 (296)

AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer

open access: yesClinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Mast cells and basophils, historically defined by their pathogenic roles in allergic diseases and type I hypersensitivity, are increasingly recognized as influential participants in cancer biology. Emerging research in AllergoOncology highlights their plasticity, diverse functions, and significance beyond classical contributions to allergy ...
Jack Alder   +6 more
wiley   +1 more source

Maternal and placental galectins: key players in the feto-maternal symbiotic tango. [PDF]

open access: yesSemin Immunopathol
Oravecz O   +9 more
europepmc   +1 more source

Galectin Structure.

open access: yesTrends in Glycoscience and Glycotechnology, 1997
Yuri D. Lobsanov, James M. Rini
openaire   +2 more sources

AS1842856 Reduces β‐Amyloid Burden via Inhibiting PLA2G4A‐Mediated Lysosomal Dysfunction in APP/PS1 Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
AS1842856 reduces intracellular levels of GSK3α/β by binding to them and promoting their exocytosis. This reduction leads to diminished GSK3β‐mediated activation of NF‐κB, resulting in decreased transcription of PLA2G4A and reduced lysosomal damage. Ultimately, this enhances lysosomal degradation of Aβ, lowering Aβ load in APP/PS1 mice.
Da‐Long He   +5 more
wiley   +1 more source

Look Who Is Talking: Extracellular Vesicles as Mediators of Intercellular and Interorgan Communication

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Extracellular vesicles (EVs) mediate intercellular and interorgan communication during both physiological and pathological conditions. EVs include exosomes, ectosomes, and apoptotic bodies and contain bioactive molecules. EVs are delivered to proximal cells or can travel in bodily fluids and reach distant organs, where they trigger a response from the ...
Michela Saviana   +4 more
wiley   +1 more source

Role of Galectin-1 in the Pathogenesis of Melanoma. [PDF]

open access: yesJ Cancer Sci Clin Ther
Kim G   +5 more
europepmc   +1 more source

Single‐cell RNA sequencing and high‐dimensional flow cytometry reveal distinct peripheral immune landscapes of type 1 autoimmune pancreatitis and pancreatic ductal adenocarcinoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Research Highlights • Illustrated the single‐cell peripheral immune landscape of AIP and its distinction from PDAC. • Identified expanded CD23+IgG4high‐switched memory B cells, Tfh cells and enhanced antigen‐presentation interactions between them. • Multi‐centre flow cytometry validated a nomogram incorporating these subsets for differential diagnosis.
Chenxiao Liu   +19 more
wiley   +1 more source

Wound‐Healing Efficacy of Garcinia pedunculata Fruit Extract: In Vivo and In Silico Validation of Regenerative Mechanisms With Histological Analysis

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study demonstrates that G. pedunculata fruit possesses potent wound‐healing activity, evidenced by accelerated wound contraction, reduced epithelialization time, enhanced fibroblast proliferation, increased collagen deposition, and improved neovascularization in both excision and burn models. ABSTRACT Garcinia pedunculata Roxb., traditionally used
Kazi Sanjida Tahrim   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy