Results 181 to 190 of about 9,887 (270)

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source

A glycosaminoglycan microarray identifies galectin-4 binding to sulfated glycosaminoglycans. [PDF]

Biochem Biophys Rep
Sano K, Nagatomo M, Shigematsu K, Yamasaki K, Anh DXT, Shibuya A, Otsuka Y, Minamisawa T, Tateno H.   +8 more
europepmc   +1 more source

Push–pull hypothesis of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 11, November 2026.
Abstract The “push–pull” hypothesis of Alzheimer's disease (AD) emerges from a careful examination of the key discoveries over the past 40 years. Specifically, amyloid beta (Aβ) plays a direct role impairing endolysosome activity in neurons and microglia, promoting the collapse of proteostasis, reducing tau degradation, and facilitating the cell‐to ...
Matthew Townsend
wiley   +1 more source

Sponge Galectins: Structure, Evolution, and Function. [PDF]

ACS Omega
Sousa ARO, Ferreira da Ponte JAD, Sampaio AH, Nagano CS, Carneiro RF.   +4 more
europepmc   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2280-2291, November 2026.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Structural and Biophysical Characterization of C-Glycosylic 1,2-Thiodisaccharides Reveals Determinants of Selective Binding to Galectin-7 and Galectin-8N. [PDF]

ChemMedChem
Tsagkarakou AS, Kantsadi AL, Theodoridou VI, Veliotis N, Lázár L, József J, Juhász L, Kontopidis G, Leffler H, Nilsson UJ, Somsák L, Leonidas DD.   +11 more
europepmc   +1 more source

Ventricular and Choroid Plexus Morphological Alterations and Their Associations With Peripheral Biomarkers in Behavioral Variant Frontotemporal Dementia

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Background Frontotemporal dementia (FTD) is a neurodegenerative disorder and a major cause of early‐onset dementia. Alterations in ventricular and choroid plexus volumes have been reported in several neurodegenerative diseases. The morphological alterations of the ventricular system and choroid plexus in behavioral variant frontotemporal ...
Ailing Yue, Qianqian He, Hua Lu, Yufei Chen, Jiahui Hou, Yuxuan Xu, Liyong Wu, Min Chu   +7 more
wiley   +1 more source

Insights into Reproductive Immunology and Placental Pathology, 2nd Edition. [PDF]

Int J Mol Sci
Szukiewicz D.
europepmc   +1 more source

Mechanistic Study of GSDME and CXCL10 in SUV39H1‐Mediated Pyroptosis and Immune Suppression in Cervical Cancer

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Cervical cancer (CC) remains a major global health challenge characterized by high incidence and mortality. The histone methyltransferase suppressor of variegation 3–9 homolog 1 (SUV39H1) has emerged as a key epigenetic regulator in tumor progression, but its role in modulating pyroptosis and remodeling of the immune microenvironment in CC ...
Li Zhang, Peiting Sheng, Dongge Cai, Ziyue Zhao, Xiaoling Wu, Yan'e Gao   +5 more
wiley   +1 more source

Galectin-3-A Multifunctional Molecule and a Key Player in Health and Disease. [PDF]

Molecules
Lupu Surlea A, Negreanu-Pirjol T, Olariu L, Negreanu-Pirjol BS, Jurja S, Lepadatu AC, Basa M, Rosoiu N.   +7 more
europepmc   +1 more source