Results 161 to 170 of about 13,626 (296)
This study presents the highly efficient heterologous production of the human blood group glycosyltransferases GTA/R176A and GTB, along with their comprehensive biochemical and kinetic characterization. Tailored enzyme cascades, involving the bacterial fucosyltransferase FutC and GTA or GTB, generate milligram quantities of various blood group ABH ...
Katja Pöstges +8 more
wiley +1 more source
Galectin-12, a member of the galectin family of animal lectins, is preferentially expressed in adipocytes. We recently reported that this galectin is localized on lipid droplets, specialized organelles for fat storage. Galectin-12 regulates lipid degradation (lipolysis) by modulating lipolytic protein kinase A (PKA) signaling.
Yang, Ri-Yao, Havel, Peter, Liu, Fu-Tong
openaire +2 more sources
Altered distribution of tissue galectins correlates with mucosal dysregulation in SIV infection. [PDF]
Premeaux TA +5 more
europepmc +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Correlation of Galectin Family Expression with Glioblastoma Progression and Survival. [PDF]
Curpen P +7 more
europepmc +1 more source
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang +9 more
wiley +1 more source
Maternal Galectins and Glucose Regulation in Pregnancy: Chronic vs. Acute Metabolic Adaptations. [PDF]
Garcia MG +12 more
europepmc +1 more source
Colorectal cancer is characterized by an immunosuppressive microenvironment that limits immunotherapy efficacy. We identify a senescence‐like state in germinal center B cells driven by the PRELID1–VDAC3 axis, which promotes IL‐7 secretion, alleviates CD8+ T‐cell exhaustion, and enhances antitumor immunity. Targeting this pathway improves responsiveness
Yuhan Liao +8 more
wiley +1 more source
Causal Relationship Between Galectins With Neuroblastoma: A Mendelian Randomization Study. [PDF]
Long C, Liang P, Liu X, Wang Y.
europepmc +1 more source

