Results 161 to 170 of about 9,659 (276)

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Galectins at the crossroads of tumor immunity, metabolism, and metastasis: mechanisms, therapeutic resistance, and translational opportunities. [PDF]

Front Immunol
Jin C, Wang W, Gao Y.
europepmc   +1 more source

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote ...
Udit Thakur, Jonathan M. Kalman
wiley   +1 more source

Galectin‐3 plasma levels are associated with left atrial contractile function in long‐distance runners

Experimental Physiology, EarlyView.
Abstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Felipe Contreras‐Briceño, Fernanda Sanhueza‐Olivares, Rodrigo Fernández, Silvana Llevaneras, Pablo F. Castro, Luigi Gabrielli, Mario Chiong   +6 more
wiley   +1 more source

Mechanisms and therapeutic implications of galectins regulating Epstein-Barr virus infection. [PDF]

Virus Res
Huang JY, Baua AD, Yang ZS, Tsui CI, Chen PC, Wang WH, Assavalapsakul W, Thitithanyanont A, Chen YH, Wang SF.   +9 more
europepmc   +1 more source

Examining the role of endothelial derived galectins in vascular inflammation [PDF]

This thesis explores how galectins, sugar-binding proteins, influence leukocyte trafficking during inflammation. Galectins (Gal) are known to be involved in inflammation, but specific endothelial-galectin interactions remain unclear.
Lightfoot, Abbey
core   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Structural Characterization of a Proto-Type Galectin from <i>Cinachyrella</i> sp. and Evaluation of Its Selective Bacterial Glycan Recognition and Antibiofilm Activity. [PDF]

Microorganisms
Marques JSN, Andrade FRN, Torres RCF, Barbosa Junior IF, Silva GSDD, Chaves RP, Malveira EA, Nascimento E, Pinheiro U, Vasconcelos MA, Texeira EH, Carneiro RF, Nagano CS, Sampaio AH.   +13 more
europepmc   +1 more source

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

Immunology, Volume 179, Issue 2, Page 269-286, October 2026.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu, Fırat Demircan, Başak Aru, Süheyla Apaydın, Abdullah Demir, Rabia Tığlı, Gürkan Tellioğlu, Ali Osman Gürol, Gülderen Yanıkkaya Demirel   +8 more
wiley   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, Volume 13, Issue 49, 3 September 2026.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source