Results 171 to 180 of about 9,887 (270)

Galectin-4: A Novel Mediator of Human Intervertebral Disc Degeneration. [PDF]

JOR Spine
Strauss C, Djojic D, Stadlmann J, Grohs JG, Alphonsus J, Schmidt S, André S, Pichler KM, Savic-Ivanovic S, Cezanne M, Rothbauer M, Windhager R, Toegel S.   +12 more
europepmc   +1 more source

Nanobiomechanics in Oncology: Atomic Force Microscopy for Cancer Mechanophenotyping Using Cellular Young's Modulus

Journal of the Royal Society of New Zealand, Volume 57, Issue 1, February 2027.
This review examines the current literature on the application of atomic force microscopy (AFM) to cancer mechanophenotyping, with particular emphasis on cellular Young's modulus and its potential diagnostic significance. A structured electronic search of PubMed, Scopus and Google Scholar was conducted to identify studies published between 1999 and ...
Hermawan Tjoa, Li Mei, Harsha De Silva, Darryl Tong, Guangzhao Guan   +4 more
wiley   +1 more source

Mechanisms and therapeutic implications of galectins regulating Epstein-Barr virus infection. [PDF]

Virus Res
Huang JY, Baua AD, Yang ZS, Tsui CI, Chen PC, Wang WH, Assavalapsakul W, Thitithanyanont A, Chen YH, Wang SF.   +9 more
europepmc   +1 more source

Methodological considerations in interpreting serum galectin‐3 as a predictor of incident type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Lingyan Chen, Dandan Weng
wiley   +1 more source

sox17 Mutagenesis Reveals Compounding Effects ofMaternal and Zygotic Contribution on Microglia Abundance

Glia, Volume 75, Issue 1, January 2027.
sox17 is a maternal effect gene impacting microglia and microglia precursor abundance. sox17 mRNA injection timed to maternal contribution rescues abundance. A CRISPR screen reveals f11r.1, gas6, and mpp1 also regulate microglia abundance. ABSTRACT Embryonic development is shaped by maternal and zygotic factors but how the interplay between these ...
Camden A. Spring, John Dennen, Dailin Gan, Jun Li, Cody J. Smith   +4 more
wiley   +1 more source

Higher Cardiorespiratory Fitness Is Associated With a Lower Burden of Metabolic Syndrome Traits: A Cross‐Sectional Analysis of 39 197 UK Adults

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11608-11620, December 2026.
ABSTRACT Aims To investigate associations of cardiorespiratory fitness (CRF) with metabolic syndrome (MetS) trait count, MetS prevalence and individual MetS traits in a large population‐based cohort. Materials and Methods This cross‐sectional study analysed data for 39 197 adults from a UK‐based independent healthcare charity (mean ± SD: age, 45.8 ± 9 ...
Scott A. Willis, Annalena Phillipp, Kevin Deighton, Christopher Goodwin, Daniel J. Cuthbertson, Shelley E. Keating, Christopher J. A. Pugh, Jonathan G. Stine, Gaël Ennequin, Alexis Couret, David J. Stensel, Guruprasad P. Aithal, Thomas Yates, James A. King   +13 more
wiley   +1 more source

Structural Characterization of a Proto-Type Galectin from <i>Cinachyrella</i> sp. and Evaluation of Its Selective Bacterial Glycan Recognition and Antibiofilm Activity. [PDF]

Microorganisms
Marques JSN, Andrade FRN, Torres RCF, Barbosa Junior IF, Silva GSDD, Chaves RP, Malveira EA, Nascimento E, Pinheiro U, Vasconcelos MA, Texeira EH, Carneiro RF, Nagano CS, Sampaio AH.   +13 more
europepmc   +1 more source

Liver Injury Due to Hormonal Contraceptives in the Modern Era

Liver International, Volume 46, Issue 12, December 2026.
ABSTRACT Background and Aims Hormonal agents and their association with liver injury remain a concern in clinical practice. This study aimed to characterise the biochemical and clinical features of hormonal agent‐associated liver injury and compare them with a control group of age‐ and gender‐matched cases of liver injury caused by non‐hormonal drugs ...
Raj Vuppalanchi, A. Sidney Barritt, Anjali Rai, Huiman Barnhardt, Sherry Gu, Yi‐Ju Li, Naga Chalasani, for the Drug‐Induced Liver Injury Network, Naga Chalasani, Marwan Ghabril, Raj Vuppalanchi, Bob Fontana, Alisa Likhitsup, Vincent Chen, Victoria Shakhin, Paul Watkins, Sid Barritt, B. B. Behera, Jacquee Simpson, Herb Bonkovsky, Dee Faust, Andrew Stolz, Lily Dara, Neil Kaplowitz, Susan Milstein, Gina Choi, Jacqueline Nguyen, Angela Yeh, Dina Halegoua‐DeMarzio, Victor Navarro, Manish Thapar, Manisha Verma, Katrin Koy‐Pan, Verma Manisha, Cynthia Miller, Angela Pallotto, Christopher Koh, Beverly Niles, Jaha Norman, Huiman Barnhart, Matthew Baum, Jiezhun Gu, Yi‐Ju Li, Michelle McClanahan‐Crowder, Jeremy Mercer, Patricia Montana, Viviana Moreno, Eilene Pham, Hoss Rostami, Sheri Ussery, Kaye Williams, Stephanie Wu, Peter Hoffmann, Kidney Diseases, José Serrano, Jay Hoofnagle, Averell H. Sherker   +56 more
wiley   +1 more source

Shikonin: From Biosynthesis and Pharmacological Mechanisms to Translational Safety and Drug Delivery

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Shikonin, biosynthesised in Boraginaceae roots from phenylalanine‐derived PHB and isoprenoid GPP, modulates redox balance, cellular stress, signalling pathways, and regulated cell death. Preclinical studies support diverse pharmacological activities, while nanocarriers improve dispersion and delivery.
Namini Joshi, Prabhakar Semwal, Balwant Rawat, Ravendra Kumar, Mozaniel Santana de Oliveira, Nishant Rai, Janhvi Mishra Rawat   +6 more
wiley   +1 more source

The role of galectins in modulating the tumor microenvironment and driving metastasis in skin cancers. [PDF]

Biol Res
Dabagh M, Ciceu A, Balta C, Trotta MC, Ferraro B, D'Amico G, Hermenean A, Voiculescu VM.   +7 more
europepmc   +1 more source