Developing immunotherapies through glycosylation reprogramming to combat solid cancers. [PDF]
Front ImmunolToyofuku T, Kumanogoh A.
europepmc +1 more source
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
Disorder of the immune and inflammatory response involving galectin-1, -3 and -7 in women with invasive breast cancer - potential importance in diagnosis and monitoring the course of the disease. [PDF]
Front OncolKrólewska-Daszczyńska P +5 more
europepmc +1 more source
MedComm, Volume 7, Issue 9, September 2026.The clinical manifestations of PFO. Although the majority of PFOs are benign and asymptomatic, they can present with a variety of clinical manifestations, or coexisting with other diseases and aggravating their symptoms, including cerebral diseases (such as CS, epilepsy, TIA, or migraine), systemic embolism (such as embolism in renal artery, coronary ...
Linlin Meng +6 more
wiley +1 more source
Galectins: Role and Therapeutics in Diabetes and Diabetic Foot Ulcers. [PDF]
BiomoleculesAlobaidi A, Judeid RA, Rai V.
europepmc +1 more source
High‐Content CRISPR Screening: Methods and Applications
MedComm, Volume 7, Issue 9, September 2026.High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans. [PDF]
Int J Mol SciFeng C +8 more
europepmc +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
MedComm, Volume 7, Issue 9, September 2026.This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source
Harnessing the endosomal escape compartment as a strategy to enhance RNA delivery via lipid nanoparticles. [PDF]
Mol Ther Nucleic AcidsBourguignon T +3 more
europepmc +1 more source
Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony
PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Karin Ljung +4 more
wiley +1 more source