Results 191 to 200 of about 9,167 (280)

Single‐cell profiling reveals peripheral blood immune landscape remodelling in breast cancer lymph node metastasis

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
scRNA‐seq reveals pro‐metastatic neutrophil and exhausted T/NK subsets in BC patients with LN metastasis. Interferon‐stimulated neutrophils secrete LGALS9, drives T/NK cell exhaustion via HAVCR2. Neutralising LGALS9 restores T‐cell anti‐tumour activity, suggesting a novel therapeutic target.
Bo Chen, Kang Ma, Yunjie Wang, Liulu Zhang, Xinyue Feng, Cheng Long, Xuejing Tan, Kun Wang   +7 more
wiley   +1 more source

Causal Relationship Between Galectins With Neuroblastoma: A Mendelian Randomization Study. [PDF]

Mol Neurobiol
Long C, Liang P, Liu X, Wang Y.
europepmc   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Maternal Galectins and Glucose Regulation in Pregnancy: Chronic vs. Acute Metabolic Adaptations. [PDF]

Diabetes Metab J
Garcia MG, Hamann E, Huhn EA, Forbes K, Roser P, Weiser-Fuchs MT, Dieberger AM, Csapo B, Obermayer-Pietsch B, Poppel MNMV, Fluhr H, Jantscher-Krenn E, Blois SM.   +12 more
europepmc   +1 more source

Low‐Dose H2O2 Priming Improves Performance Under Simulated Marine Heatwave Conditions in a Coastal Bivalve

Global Challenges, Volume 10, Issue 6, June 2026.
Low‐dose hydrogen peroxide priming shapes Manila clam responses to simulated marine heatwaves, which showed faster burrowing behavior, limited transcriptional disruption, and reduced opportunistic microbiota. A long‐term field trial confirms no detectable adverse effects, supporting redox‐based chemical priming as a feasible resilience strategy in ...
Chiara Mascitelli, Giovanna Monticelli, Alessandro Nardi, Giulia Dalla Rovere, Graziano Rilievo, Ilaria Bernardini, Nicole Macrì, Deborah Cesaroni, Valentina Tavolazzi, Gabriele Andreatta, Tomaso Patarnello, Luca Bargelloni, Luca Peruzza, Maura Benedetti, Massimo Milan   +14 more
wiley   +1 more source

Modified citrus pectin modulates splenic immune responses and galectin expression following cisplatin treatment in Wistar rats. [PDF]

J Mol Histol
Dias Dos Santos D, da Silva Neto AF, de Chiara LS, Corrêa MP, da Silva-Sasso GR, Sanches JM, Florencio-Silva R, Oyama LM, Gil CD.   +8 more
europepmc   +1 more source

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

Glia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar, Yuki Takeuchi, Ichiro Masai   +2 more
wiley   +1 more source

Evolution of intrinsically disordered regions in vertebrate galectins for phase separation. [PDF]

EMBO Rep
Lin YH, Chen YC, Sun YC, Huang JR.
europepmc   +1 more source

Targeting the Galectin Axis in Osteoarthritis: Chondroprotective Effects of Dietary and Pharmacological Phytochemicals. [PDF]

Molecules
Pichler KM, Kottinger S, Rodriguez Molina B, Alphonsus J, Schmidt S, Windhager R, Kaltner H, Rothbauer M, Toegel S.   +8 more
europepmc   +1 more source

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, Volume 2, Issue 2, June 2026.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source