Results 191 to 200 of about 9,887 (270)

Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44 [PDF]

Chembiochem
CD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
Payá‐García M, Rojas‐Marcos J, Bermejo I, Del Balzo D, Ardá A, Unione L, Jiménez‐Barbero J, Gimeno A.   +7 more
europepmc   +2 more sources

Compressive Goiter Hiding Clear Cell Renal Cell Carcinoma Metastases to the Thyroid Gland—Report of a Rare Case and Literature Review

Clinical Case Reports, Volume 14, Issue 11, November 2026.
Histological section (hematoxylin and eosin, 40× magnification) of the total thyroidectomy specimen showing the presence of characteristic compact nests and cellular sheets with clear or eosinophilic cytoplasm, diagnostic for secondary involvement of the thyroid gland by clear cell renal cell carcinoma.
Chuyao Ying, Henrique Messias, Carlos Zagalo, Saudade André, Pedro Gomes   +4 more
wiley   +1 more source

The Proto Type Galectin Drgal1-L2 from Zebrafish Hinders Infection by the Infectious Hematopoietic Necrosis Virus by Binding to Its Glycosylated Receptors on the Epithelial Cell Surface. [PDF]

Biomolecules
Abernathy K, Wang S, Feng C, Mancini J, Zong G, González-Montalbán N, Wang LX, Vasta GR.   +7 more
europepmc   +1 more source

Right Ventricular Dysfunction and Ventriculo‐Arterial Uncoupling in Heart Failure With Preserved Ejection Fraction: A Phenotype‐Specific Review of Mechanisms, Diagnosis, and Therapeutic Strategies

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun, Talha Farooq, Suhayya Batool, Sadia Tameez‐ud—din, Muhammad Yousaf, Preet Memon, Mohsin Ali, Arun Kumar Maloth, F. N. U. Sawaira, Muhammad Taimur Khan, Mohammad Eisa Ali, Mansoor Khalid, Maleeha Pandit, Kamil Ahmad Kamil   +13 more
wiley   +1 more source

Glycosylation Encodes Selective Galectin Recognition and Signaling by Osteopontin. [PDF]

JACS Au
Bermejo IA, Balzo DD, Azkargorta M, Marina A, Delgado S, Gimeno A, Peccati F, Diercks T, Elortza F, Millet O, Ardá A, Mateos B, Jiménez-Barbero J, Unione L.   +13 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Abnormal Galectin Signaling in the Pathomechanisms of Placental Dysfunction in Gestational Diabetes Mellitus. [PDF]

Int J Mol Sci
Szukiewicz D.
europepmc   +1 more source

Site‐specific O‐glycans influence lacritin structure and multimerization in tears

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang, Ryan J. Chen, Isaac Lian, Madilynn Hamilton, Keira E. Mahoney, Jeff Romano, Gordon Laurie, Stacy A. Malaker   +7 more
wiley   +1 more source

Galectin-8 binds HIV envelope glycoproteins with high affinity and promotes viral infectivity. [PDF]

Front Cell Infect Microbiol
Sheik-Khalil E, Kahl-Knutson B, Johansson E, Karlson S, Nilsson UJ, Leffler H, Jansson M.   +6 more
europepmc   +1 more source

Exercise‐Based Management of Diabetic Cardiomyopathy: Preclinical Mechanisms, Clinical Evidence, and Translational Strategies

Journal of Diabetes, Volume 18, Issue 11, November 2026.
Exercise may mitigate diabetic cardiomyopathy by improving mitochondrial metabolism, redox balance, calcium handling, and inflammatory‐fibrotic remodeling. Translation into clinical practice requires phenotype‐ and risk‐adapted exercise prescriptions, standardized dose reporting, and multimodal monitoring to define safety, efficacy, and long‐term ...
Xiaoya Li, Zhiqiang Wang, Jingjing Liu
wiley   +1 more source