Results 91 to 100 of about 78,261 (320)

Are histological alterations observed in the gallbladder precancerous lesions?

Clinics, 2010
INTRODUCTION: Gallbladder cancer, which is characterized by rapid progression and a poor prognosis, is a complex disease to treat. Unfortunately, little is known currently about its etiology or pathogenesis.
Adriana Lúcia Agnelli Meirelles-Costa, Claudio José Caldas Bresciani, Rodrigo Oliva Perez, Barbara Helou Bresciani, Sheila Aparecida C. Siqueira, Ivan Cecconello   +5 more
doaj   +1 more source

Global Burden of Disease Due to High Body Mass Index and Projections to 2040: A Study Based on the Global Burden of Disease Study 2019

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background The prevalence of high body mass index (BMI) contributes to an increased risk of various diseases. This study aimed to identify global disease burden trends associated with high BMI from 1990 to 2019 and forecasts up to 2040. Methods Using data from the global burden of disease (GBD) 2019 study, we analysed the number and ratio of ...
Eun‐Ji Kim, Yoonseo Park, Sewon Park, Mihajlo Jakovljevic, Munjae Lee   +4 more
wiley   +1 more source

Risk factors for gallbladder cancer

Journal of Education, Health and Sport, 2020
Introduction and purpose:                Gallbladder cancer is the most common neoplasm of the bile duct. Early GBC is usually asymptomatic, but is prone to early metastases. This means that most GBC cases are diagnosed very late, and this contributes to the poor prognosis of this disease.
Magdalena Suchodolska, Blanka Świerczyńska, Adrian Undziakiewicz, Krzysztof Smoluchowski, Michał Sekuła   +4 more
openaire   +4 more sources

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

International Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk, Emma L. Kaderly Rasmussen, Charlotte Gerd Hannibal, Rasmus Hertzum‐Larsen, Louise Baandrup, Susanne K. Kjær   +5 more
wiley   +1 more source

EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types [PDF]

, 2017
The enhancer of zeste homolog 2 (EZH2) gene encodes a histone methyltransferase that is a catalytic subunit of the Polycomb repressive complex 2 (PRC2) group of proteins that act to repress gene expression.
Crea, Francesco, Fornaro, Lorenzo, Landi, Stefano, Paolicchi, Elisa, Rigas, Sushilaben   +4 more
core   +2 more sources

Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer

BMC Cancer, 2010
Background Biliary tract cancers have limitations in information about different location-related pathogenesis and clinico-pathological characteristics.
You Young, Kim Dong-Goo, Chung Eun-Seon, Lee Myung, Won Hye, Hong Tae, Lee In-Seok   +6 more
doaj   +1 more source

Associations of sarcopenia, sarcopenia components and sarcopenic obesity with cancer incidence: A prospective cohort study of 414,094 participants in UK Biobank

International Journal of Cancer, EarlyView.
What's New? Sarcopenia is highly prevalent and associated with adverse outcomes in cancer survivors. However, evidence regarding the role of sarcopenia in the general population as a potential risk factor for cancer development is scarce. This prospective cohort study investigated the association of sarcopenia with the incidence of 19 cancers in a ...
Panagiotis Filis, Christos K. Papagiannopoulos, Georgios Markozannes, Christos V. Chalitsios, Ioannis Zerdes, Antonios Valachis, Christopher Papandreou, Sofia Christakoudi, Konstantinos K. Tsilidis   +8 more
wiley   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Del Pozo, Reginals, Jüngst, Dieter, Lange, Volker, Miquel, Juan Francisco, Paumgartner, Gustav, Ritter, Christoph von   +5 more
core   +1 more source

Gallbladder cancer: epidemiology and outcome

Clinical Epidemiology, 2014
Gallbladder cancer, though generally considered rare, is the most common malignancy of the biliary tract, accounting for 80%-95% of biliary tract cancers. An early diagnosis is essential as this malignancy progresses silently with a late diagnosis, often proving fatal.
Rajveer Hundal, Eldon A. Shaffer
openaire   +5 more sources

Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double‐blind, randomized controlled DHA‐WIN trial

International Journal of Cancer, EarlyView.
What's New? Omega‐3 docosahexaenoic acid (DHA) has shown pleiotropic anti‐cancer effects both in vitro and in animal models. However, clinical evidence of DHA efficacy is limited. This randomized, double‐blind, placebo‐controlled trial tested the efficacy of supplementation with DHA 4.4 g/day during 18 weeks of breast cancer neoadjuvant chemotherapy ...
Jaqueline Munhoz, Marnie Newell, Gilbert Bigras, Susan Goruk, Anil Abraham Joy, Sunita Ghosh, Kerry S. Courneya, Vera Mazurak, Claire M. Douglas, Xiaofu Zhu, Bohdarianna Zorniak, John Mackey, Judith Meza Junco, Julie Price Hiller, Karen King, Sanraj K. Basi, Catherine J. Field   +16 more
wiley   +1 more source