Results 41 to 50 of about 4,466,693 (321)

Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

Molecular Cancer, 2019
The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an oncogenic regulator of several cancers. However, its expression and function in gallbladder cancer (GBC) remain largely unknown.
Jianan Chen, Yan Yu, Hua Li, Qiuyue Hu, Xiaolong Chen, Yuting He, Chen Xue, Fang Ren, Z. Ren, Juan Li, Liwen Liu, Z. Duan, G. Cui, R. Sun   +13 more
semanticscholar   +1 more source

Disease Burden of Gallbladder Cancer in China from 1990 to 2019 and the Analysis of Its Future Trends [PDF]

Zhongguo quanke yixue
Background Gallbladder cancer is featured by difficult early detection, poor treatment effectiveness and high mortality. An in-depth epidemiology research of gallbladder cancer can provide valuable data for the formulation of prevention and treatment ...
LIU Shanshan, LI Chuyi, ZHENG Ying, LU Lixia, LI Bin, YU Xiaohui, DANG Zheng
doaj   +1 more source

Long noncoding RNA PVT1 promoted gallbladder cancer proliferation by epigenetically suppressing miR-18b-5p via DNA methylation

Cell Death and Disease, 2020
Gallbladder cancer (GBC) accounts for 85–90% malignancies of the biliary tree worldwide. Considerable evidence has demonstrated that dysregulation of lncRNAs is involved in the progression of cancer.
Longyang Jin, Qiang Cai, Shouhua Wang, Shuqing Wang, Jian-dong Wang, Z. Quan   +5 more
semanticscholar   +1 more source

IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

Translational Oncology, 2023
Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu, Jingli Cai   +7 more
doaj  

EGFR-targeted fluorescent imaging using the da Vinci® Firefly™ camera for gallbladder cancer

World Journal of Surgical Oncology, 2022
Background Fluorescent imaging may aid with the precise diagnosis and treatment of patients with gallbladder cancer. In this study, we sought to demonstrate whether the da Vinci® surgical system and Firefly™ camera could detect EGFR-targeted fluorescent ...
Jung Ha Choi, Chang Moo Kang, Jeong Youp Park   +2 more
doaj   +1 more source

The global, regional, and national burden of gallbladder and biliary tract cancer and its attributable risk factors in 195 countries and territories, 1990 to 2017: A systematic analysis for the Global Burden of Disease Study 2017

Cancer, 2021
The global burden of gallbladder and biliary tract cancer (GBTC) is increasing. A comprehensive evaluation of the burden is crucial to improve strategies for GBTC prevention and treatment.
Guoqing Ouyang, Qiang Liu, Yongrong Wu, Zhen Liu, Wuchang Lu, Shuai Li, Guangdong Pan, Xiang Chen   +7 more
semanticscholar   +1 more source

Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer

Journal of Experimental & Clinical Cancer Research, 2017
Background Patients with metastatic or relapsed gallbladder cancer generally have a poor prognosis. Therefore, targeting metastasis is one arm of therapeutic strategies to treat gallbladder cancer.
Fei Zhang, Qiang Ma, Zihang Xu, Haibin Liang, Huaifeng Li, Yuanyuan Ye, Shanshan Xiang, Yijian Zhang, Lin Jiang, Yunping Hu, Zheng Wang, Xuefeng Wang, Yong Zhang, Wei Gong, Yingbin Liu   +14 more
doaj   +1 more source

RadFormer: Transformers with Global-Local Attention for Interpretable and Accurate Gallbladder Cancer Detection [PDF]

arXiv, 2022
We propose a novel deep neural network architecture to learn interpretable representation for medical image analysis. Our architecture generates a global attention for region of interest, and then learns bag of words style deep feature embeddings with local attention.
arxiv  

Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer

Journal of Cancer, 2020
Gallbladder cancer is one of the most common malignant tumors in the biliary tract. In recent years, the chemotherapy treatment for gallbladder carcinoma has exhibited obvious characteristics of drug resistance and insensitivity, and one of the main ...
Li-qiang Qian, Hao-yuan Su, Gang Wang, Bin Li, Gen-hai Shen, Quan-gen Gao   +5 more
semanticscholar   +1 more source

Randomized phase III study of gemcitabine, cisplatin plus S‐1 versus gemcitabine, cisplatin for advanced biliary tract cancer (KHBO1401‐ MITSUBA)

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 30, Issue 1, Page 102-110, January 2023., 2023
Ioka and colleagues present the results of a phase III study comparing gemcitabine and cisplatin plus S‐1 (GCS) with gemcitabine and cisplatin for unresectable or recurrent biliary tract cancer. GCS demonstrated survival benefits and a higher response rate, and could be the new standard chemotherapy for advanced biliary tract cancer.
Tatsuya Ioka, Masashi Kanai, Shogo Kobayashi, Daisuke Sakai, Hidetoshi Eguchi, Hideo Baba, Satoru Seo, Akinobu Taketomi, Tadatoshi Takayama, Hiroki Yamaue, Masahiro Takahashi, Masayuki Sho, Keiko Kamei, Jiro Fujimoto, Masanori Toyoda, Junzo Shimizu, Takuma Goto, Yoshitaro Shindo, Kenichi Yoshimura, Etsuro Hatano, Hiroaki Nagano, Kansai Hepatobiliary Oncology Group (KHBO)   +21 more
wiley   +1 more source