Results 81 to 90 of about 4,498,628 (333)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Play-Based Learning With Games as a Dance Teaching Tool

open access: yesHarmonia: Journal of Arts Research and Education
This case study focuses on Play-based Learning with game elements as a new dance teaching tool for young children. The research objective is to verify that the majority of games used by teachers in Malaysian preschools are based on guided play, which ...
Nurafiqah Diyanah Azmi, Sang Woo Ha
doaj   +1 more source

Pitako - Recommending Game Design Elements in Cicero [PDF]

open access: yes2019 IEEE Conference on Games (CoG), 2019
Paper accepted in the IEEE Conference on Games 2019 (COG 2019)
Machado, Tiago   +3 more
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Gamification in spoken language pedagogy: Indonesian EFL teachers

open access: yesJournal on English as a Foreign Language
Gamification enhances student engagement and learning through problem-solving, storytelling, competition, and rewards, but its success depends on having well-trained teachers.
Nurlaila Nurlaila   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Gameization of Educational Process in the Assessments of Students and Teachers

open access: yesВысшее образование в России
The article is devoted to the study of significance, role and potential risks of the gameization of educational processes in higher education institutions in the context of digital transformation of society and the emergence of new requests to ...
V. A. Sagaidak   +2 more
doaj   +1 more source

Gamification as a Sustainable Source of Enjoyment During Balance and Gait Exercises

open access: yesFrontiers in Psychology, 2019
We may be motivated to engage in a certain motor activity because it is instrumental to obtaining reward (e.g., money) or because we enjoy the activity, making it intrinsically rewarding.
Katinka van der Kooij   +7 more
doaj   +1 more source

Resources for Sale: Corruption, Democracy and the Natural Resource Curse [PDF]

open access: yes, 2008
A puzzling piece of empirical evidence suggests that resource-abundant countries tend to grow slower than their resource-poor counterparts. We attempt to explain this phenomenon by developing a lobbying game in which rent seeking firms interact with ...
Bulte, E.H., Damania, R.
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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