Results 201 to 210 of about 110,079 (354)

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

open access: yesBrain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García   +13 more
wiley   +1 more source

Perfluorooctanesulfonic acid (PFOS) antagonizes gamma-aminobutyric acid (GABA) receptors in larval zebrafish and mammalian models. [PDF]

open access: yesToxicol Sci
Owen R   +11 more
europepmc   +1 more source

Release of immunoreactive somatostatin from hypothalamic cells in culture: inhibition by gamma-aminobutyric acid. [PDF]

open access: bronze, 1980
R. Gamse   +5 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Evaluation of the pollution pressures posed by groups of chemicals on British riverine invertebrate populations

open access: yesBiological Reviews, EarlyView.
ABSTRACT Globally, rivers receive a diverse range of chemicals, including metals, pesticides, persistent organic pollutants, petrochemicals, human and veterinary pharmaceuticals and personal care products. However, the extent to which these different chemical groups affect riverine invertebrate communities is not well defined.
Imogen P. Poyntz‐Wright   +2 more
wiley   +1 more source

Design, synthesis and characterization of novel gamma‑aminobutyric acid type A receptor ligands

open access: diamond, 2020
Kamal Prakash Pandey   +14 more
openalex   +2 more sources

A complex network perspective on brain disease

open access: yesBiological Reviews, EarlyView.
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley   +1 more source

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