Results 241 to 250 of about 110,079 (354)

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Brain glutamate and gamma-aminobutyric acid levels across COVID-19 lockdowns in patients with recurrent major depressive disorder and healthy individuals. [PDF]

Sci Rep
Popper V, Spurny-Dworak B, Unterholzner J, Reed M, Wechsler T, Kautzky A, Stöhrmann P, Klöbl M, Mühlberger A, Frey R, Rujescu D, Lanzenberger R, Vanicek T.   +12 more
europepmc   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source

Reduced content of gamma-aminobutyric acid enhances resistance to bacterial wilt disease in tomato. [PDF]

Plant Biotechnol J
Zhao A, Li Q, Meng P, Liu P, Wu S, Lang Z, Song Y, Macho AP.   +7 more
europepmc   +1 more source

BindingDB Entry 5324: SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.

, 2012
Guy Griebel, Ghislaine Perrault, Jacques Simiand, Caroline Cohen, Pascal Granger, M. Decobert, Dominique Françon, Patrick Avenet, H. Depoortere, Suon Tan, A. Oblin, H. Schoemaker, Yannick Evanno, Mireille Sevrin, Pascal George, B. Scatton   +15 more
openalex   +1 more source

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

Epilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong, Hyun‐Kyoung Lim, Hayeon Kim, Juheon Lee, Siyoon Lee, Minah Suh   +5 more
wiley   +1 more source

Alterations in gamma-aminobutyric acid and glutamate neurotransmission linked to intermittent theta-burst stimulation in depression: a sham-controlled study. [PDF]

Transl Psychiatry
Steinholtz L, Bodén R, Wall A, Lubberink M, Fällmar D, Persson J.   +5 more
europepmc   +1 more source

Response Surface Modeling for the Enrichment of Gamma‐Aminobutyric Acid with a Minimum Content of Citrinin in Monascus‐Fermented Rice

, 2019
Washim Khan, Omkar Regmi, Mojeer Hasan, Bibhu Prasad Panda   +3 more
openalex   +1 more source

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel, Chaitali Ghosh, Kathryn Bisaha, Jean Khoury, Ashley Nemes‐Baran, Ingmar Blumcke, Imad Najm   +6 more
wiley   +1 more source

Involvement of Matrix Metalloproteinases (MMP-2 and MMP-9), Inflammasome NLRP3, and Gamma-Aminobutyric Acid (GABA) Pathway in Cellular Mechanisms of Neuroinflammation in PTSD. [PDF]

Int J Mol Sci
Grzesińska A, Ogłodek EA.
europepmc   +1 more source