Results 51 to 60 of about 94,242 (328)

A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro [PDF]

, 2004
Basic cellular and network mechanisms underlying gamma frequency oscillations (30–80 Hz) have been well characterized in the hippocampus and associated structures.
A. Bibbig, A. Roopun, A. Vogt, Brumberg, Buhl, Catania, Cunningham, Draguhn, E. H. Buhl, F. E. N. LeBeau, Fisahn, Galarreta, Gibson, Gray, Grenier, H. Monyer, Hormuzdi, Lampl, Llinas, M. A. Whittington, M. O. Cunningham, Nowak, R. D. Traub, Schmitz, Segal, Steriade, Steriade, Tamas, Tam  s, Traub, Traub, Varela, Whittington, Whittington   +33 more
core   +3 more sources

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing

Advanced Sensor Research, EarlyView.
A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson, Rajeev Kumar, Amit Kumar Shringi, Hazel Achieng Ouma, Pooja D. Walimbe, Fei Yan   +5 more
wiley   +1 more source

Effects of insecticidal ketones present in mint plants on GABA A receptor from mammalian neurons [PDF]

, 2017
The genus Mentha, an important member of the Lamiaceae family, is represented by many species commonly known as mint. The insecticidal activity of Mentha oil and its main components has been tested and established against various insects/pests.
Delgado Marín, Leticia Ester, Garcia, Daniel Asmed, Sánchez, Mariela Eugenia   +2 more
core   +2 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Temporal coding at the immature depolarizing GABAergic synapse

Frontiers in Cellular Neuroscience, 2010
In the developing hippocampus, GABA exerts depolarizing and excitatory actions and contributes to the generation of neuronal network driven Giant Depolarizing Potentials (GDPs).
Guzel Valeeva, Guzel Valeeva, Azat Abdullin, Azat Abdullin, Azat Abdullin, Roman Tyzio, Andrei Skorinkin, Evgeny Nikolski, Yehezkiel Ben-Ari, Rustem Khazipov   +9 more
doaj   +1 more source

Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain : a systematic review [PDF]

, 2015
Background: Chronic neck pain is a common problem with a poorly understood pathophysiology. Often no underlying structural pathology can be found and radiological imaging findings are more related to age than to a patient's symptoms.
Bramer, Wichor, Cagnie, Barbara, Danneels, Lieven, Dolphens, Mieke, Kregel, Jeroen, Kuipers, Mandy, Malfliet, Anneleen, Meeus, Mira, Nijs, Jo, Roussel, Nathalie   +9 more
core   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

Advanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua, Ning Ding, Yiming Hua, Xiaoke Wang, Yu Xu, Xiangrui Qiao, Xue Shi, Ting Bai, Ying Xiong, Xiaozhen Zhuo, Chong Fan, Juan Zhou, Yue Wu, Junhui Liu, Zuyi Yuan, Ting Li   +15 more
wiley   +1 more source