Results 161 to 170 of about 511,405 (214)
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Change of Phase-Solubility Behavior by Gamma-Cyclodextrin Derivatization
Pharmaceutical Research, 1985The effect of γ-cyclodextrin and its four derivatives on the solubility of progesterone in phosphate buffer pH 7.4 was investigated. γ-Cyclodextrin forms a complex precipitating from solution at low cyclodextrin concentrations. No precipitation of complexes was observed with the γ-cyclodextrin derivatives.
B W, Müller, U, Brauns
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Modification of the apparent lipophilicity of steroidal drugs with gamma-cyclodextrin
European Journal of Pharmaceutics and Biopharmaceutics, 1998The interaction between 17 steroidal drugs and gamma-cyclo-dextrin (gamma-CD) was determined by charge-transfer chromatography and the relative strength of interaction was calculated. The relationship between the strength of interaction and the physico-chemical parameters of steroidal drugs was elucidated with principal component analysis.
T, Cserháti, E, Forgács
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Safety assessment of gamma-cyclodextrin.
Regulatory toxicology and pharmacology : RTP, 2004Gamma-cyclodextrin (gamma-CD) is a cyclic alpha-(1,4)-linked oligosaccharide consisting of eight glucose molecules. Like other cyclodextrins, gamma-CD can form inclusion complexes with a variety of organic molecules because the inner side of the torus-like molecule is less polar than the outer side.
I C, Munro +3 more
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The Journal of Physical Chemistry, 1989
A partir de la dependance de la fluorescence du pyrene (Py) dans la γ-cyclodextrine (γ-CD) vis-a-vis du pH, on montre que la fluorescence est entierement due a un compose d'inclusion 2:2 de γ-CD avec Py. Mise en evidence egalement de composes d'inclusion 1:1 et 1:2 Py-γ-CD.
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A partir de la dependance de la fluorescence du pyrene (Py) dans la γ-cyclodextrine (γ-CD) vis-a-vis du pH, on montre que la fluorescence est entierement due a un compose d'inclusion 2:2 de γ-CD avec Py. Mise en evidence egalement de composes d'inclusion 1:1 et 1:2 Py-γ-CD.
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Enhancement of selectivity for producing gamma-cyclodextrin.
Applied biochemistry and biotechnology, 2000The production of cyclodextrins (CDs) by cyclodextrin-glycosyl-transferase (CGTase) from Bacillus firmus was studied, with respect to the effect of the source of starch upon CD yield and on the selectivity for producing gamma-CD. Cyclodextrin production tests were run for 24 h at 50 degrees C, pH 8.0, and 1 mg/L of CGTase, and substrates were ...
G, Matioli, G M, Zanin, F F, de Moraes
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Isolation and Purification of Gamma-Cyclodextrin by Affinity Chromatography
1988An affinity chromatographic process for purification of gamma-cyclodextrin (CD) was developed. It was based on a specific inclusion complex formation between 1,8-naphthylic acid anhydride coupled to aminated Biogel P-6. This gel completely separated gamma-CD from other CDs and from acyclic dextrins. The capacity of one liter of the gel was more than 20
Pekka Mattsson +2 more
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Colorimetric determination of .gamma.-cyclodextrin
Analytical Chemistry, 1984Takashi. Kato, Koki. Horikoshi
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