Results 141 to 150 of about 9,031 (203)
Autoimmune Gastritis Associated With a Gastric Hyperplastic Polyp: Two Case Reports and Review of its Neoplastic Potential. [PDF]
Lee MH, Kim SE, Park MI, Jung K.
europepmc +1 more source
The diagnostic value of angiotensin, g-GT, blood lactate, and renal resistance index combined detection in acute kidney injury after neonatal asphyxia. [PDF]
Shi X, Dai L, Wang Y, Deng F.
europepmc +1 more source
Case Report: Marchiafava-Bignami disease: anti-parietal cell antibodies as a potential etiological factor in a novel case presentation. [PDF]
Zhang J +15 more
europepmc +1 more source
Three-Dimensional Models in Hepatic Surgery: Clinical Outcomes A Single-Center Experience. [PDF]
Vieiro Medina MV +6 more
europepmc +1 more source
Gamma-glutamyl hydrolase and drug resistance
Gamma-glutamyl hydrolase (GGH) is a lysosomal enzyme involved in the metabolism of folates and anti-folates. It acts as an endo- and/or exo-peptidase to cleave gamma-polyglutamate chains that are attached to folates and anti-folates after they enter a mammalian cell.
Erasmus Schneider, Thomas J. Ryan
exaly +5 more sources
Gamma-glutamyltranspeptidases (gamma-GTs) catalyze the transfer of the gamma-glutamyl moiety of glutathione and related gamma-glutamyl amides to water (hydrolysis) or to amino acids and peptides (transpeptidation) and play a key role in glutathione metabolism.
Immacolata Castellano +3 more
exaly +7 more sources
AbstractContext: Acute lymphoblastic leukemia patients show differences in methotrexate-induced toxicity after treatment with this anti-cancer drug. Pharmacogenetics is an important determining factor for toxicity diversity. Objective: In this study, the effect of +452 CT and ˗ 401CT polymorphisms of Gamma-glutamyl hydrolase (GGH) gene on methotrexate ...
Abolfazl Kalantari +4 more
exaly +4 more sources
Extranodal extension (ENE) is an important prognostic factor in oral squamous cell carcinoma (OSCC). However, ENE is only confirmed postoperatively by histologic assessment of the lymph nodes after neck dissection. Accurate identification of ENE preoperatively would help in management of OSCC.We determined the expression of molecular markers gamma ...
Nor Aszlitah Burhanudin +6 more
openalex +4 more sources
Poor neoplastic differentiation contributes to the rapid progression of uterine corpus endometrial carcinoma (UCEC). Thus, it is essential to identify candidate genes, clarifying the carcinogenesis and progression of UCEC.We screened genes that affect differentiation and prognosis in UCEC.
Cheng Zhu +12 more
openalex +3 more sources

