Indirect treatment comparison of dabrafenib plus trametinib versus vemurafenib plus cobimetinib in previously untreated metastatic melanoma patients. [PDF]
, 2017 BackgroundMetastatic melanoma is an aggressive form of skin cancer with a high mortality rate and the fastest growing global incidence rate of all malignancies.
Ahuja, Amit +4 more
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Serum γ-Glutamyl Transferase Is Inversely Associated with Bone Mineral Density Independently of Alcohol Consumption [PDF]
Endocrinology and Metabolism, 2016 Backgroundγ-Glutamyl transferase (GGT) is a well-known marker of chronic alcohol consumption or hepatobiliary diseases. A number of studies have demonstrated that serum levels of GGT are independently associated with cardiovascular and metabolic ...
Han Seok Choi +3 more
doaj +1 more source
Gamma‐glutamyltransferase—friend or foe within? [PDF]
Liver International, 2016 AbstractGamma‐glutamyltransferase (GGT) is a liver enzyme, which is located on the plasma membranes of most cells and organ tissues, but more commonly in hepatocytes, and is routinely used in clinical practice to help indicate liver injury and as a marker of excessive alcohol consumption. Among the liver enzymes, important advances have especially been
openaire +3 more sources
Serum γ-glutamyltransferase, alanine aminotransferase and aspartate aminotransferase activity in healthy blood donor of different ethnic groups in Gorgan [PDF]
, 2016 Introduction: Measure of liver enzymes may help to increase safety of blood donation for both blood donor and recipient. Determination of liver enzymes may prepare valuable clinical information.
Marjani, A. +2 more
core +1 more source
Evaluation of hepatotoxic properties of pyrimidine derivatives
Сибирский научный медицинский журнал, 2022 The aim of the study was to evaluate the hepatotoxic properties of new pyrimidine derivatives 3-[2-(1-naphthyl)-2- oxoethyl]-6-bromoquinazoline-4(3H)-oh (VMA–13–06), 3-(2-tert-butyl-2-oxoethyl)quinazoline-4(3H)-one (VMA-13- 11) and 3-(2-isopropyloxy-2 ...
A. L. Yasenyavskaya +3 more
doaj +1 more source
A High Performance Gel Filtration Chromatography Method for gamma-Glutamyltransferase Fraction Analysis [PDF]
, 2008 The clinical relevance of serum c-glutamyltransferase (GGT) activity, in areas other than hepatic function, has recently been increased by several epidemiological associations.
Aldo Paolicchi +9 more
core +1 more source
Serum Gamma-Glutamyltransferase Levels Predict Clinical Outcomes in Hemodialysis Patients. [PDF]
PLoS ONE, 2015 Gamma-glutamyltransferase (GGT) is a biomarker of liver injury. GGT has also been reported to be a marker of oxidative stress and a predictor of mortality in the general population. Hemodialysis (HD) patients suffer from oxidative stress.
Woo Yeong Park +12 more
doaj +1 more source
Additive effect of non-alcoholic fatty liver disease on metabolic syndrome-related endothelial dysfunction in hypertensive patients [PDF]
, 2016 Metabolic syndrome (MS) is characterized by an increased risk of incident diabetes and cardiovascular (CV) events, identifying insulin resistance (IR) and endothelial dysfunction as key elements.
Caroleo, B +6 more
core +2 more sources
Serum alkaline phosphatase and γ-glutamyl transferase in acute pyelonephritis
Kidney Research and Clinical Practice, 2019 Background : Elevated serum alkaline phosphatase (AP) and γ-glutamyl transferase (γ-GT) are commonly observed in patients with acute pyelonephritis. The goal of this study was to examine the clinical significance of elevated serum AP and γ-GT levels and
Chaehoon Han +9 more
doaj +1 more source
Effects of Chronic Kidney Disease on Liver Enzymes Activity During Pre and Post Hemodialysis
Journal of Nobel Medical College, 2020 Background: Worldwide chronic kidney disease is one of the primary public health problems. This study aimed to find the activity of liver enzymes alanine aminotransferase, aspartate transaminase, alkaline phosphatase, and Gamma-glutamyl transferase in ...
Sanjay Kumar Jha +2 more
doaj +1 more source