Results 131 to 140 of about 11,895 (194)

Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606. [PDF]

Alzheimers Dement
Godoy-Lugo JA, Thorwald MA, Cacciottolo M, D'Agostino C, Chakhoyan A, Sioutas C, Tanzi RE, Rynearson KD, Finch CE.   +8 more
europepmc   +1 more source

P2‐337: Characterization of the affinity of GSI‐953 for binding to gamma‐secretase and comparison to benchmark gamma‐secretase inhibitors [PDF]

Alzheimer's & Dementia, 2008
Anthony F. Kreft, Magid A. Abou-Gharbia, Ann E. Aulabaugh, Kevin P. Atchison, George Diamantidis, Boyd L. Harrison, Warren D. Hirst, Xinyi Huang, Dennis M. Kubrak, Kerri Lipinski, Ronald L. Magolda, Robert L. Martone, Michael K. May, Scott C. Mayer, Menelas N. Pangalos, Alex M. Porte, Peter H. Reinhart, Lynn Resnick, Hua Zhou, J. Steven Jacobsen   +19 more
openaire   +1 more source

New onset hidradenitis suppurativa and eruptive milia associated with gamma secretase inhibitor therapy in a patient with desmoid tumor: A case report. [PDF]

JAAD Case Rep
Gutierrez Y, DeClerck B, Hsiao JL, Lee KH.   +3 more
europepmc   +1 more source

DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment. [PDF]

Adv Pharm Bull, 2021
Kumari M, Krishnamurthy PT, Pinduprolu SKSS, Sola P.   +3 more
europepmc   +1 more source

A novel generation of potent gamma-secretase modulators: Combat Alzheimer's disease and Down syndrome-associated Alzheimer's disease. [PDF]

Neural Regen Res
Chen XQ.
europepmc   +1 more source

PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer's disease. [PDF]

Acta Neuropathol Commun
Perrin F, Anderson LC, Mitchell SPC, Sinha P, Turchyna Y, Maesako M, Houser MCQ, Zhang C, Wagner SL, Tanzi RE, Berezovska O.   +10 more
europepmc   +1 more source

Use of an Intramolecular Quenched Fluorescence (IQF) Cleavage Assay for Assessing Enzyme Kinetics of Gamma-Secretase in Human Skin Fibroblasts and Keratinocytes. [PDF]

Methods Mol Biol
Badiei B, Garza LA.
europepmc   +1 more source

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates. [PDF]

J Exp Med, 2020
Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C.   +14 more
europepmc   +1 more source

Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites. [PDF]

J Biol Chem
Perrin F, Sinha P, Mitchell SPC, Sadek M, Maesako M, Berezovska O.   +5 more
europepmc   +1 more source

Gamma-Secretase Subunit PEN-2 [PDF]

, 2020
openaire   +1 more source