Results 91 to 100 of about 13,834,757 (208)

A subset of IL-10-producing gammadelta T cells protect the liver from Listeria-elicited, CD8(+) T cell-mediated injury

, 2008
Although gammadelta T cells play a role in protecting tissues from pathogen-elicited damage to bacterial, viral and parasitic pathogens, the mechanisms involved in the damage and in the protection have not been clearly elucidated. This has been addressed
Katherine A. Rhodes, Andrew, Elizabeth, Rhodes, Katherine A., Newton, Darren J, Newton, Darren J., Andrew, Elizabeth M, Tramonti, Daniela, Andrew, Elizabeth M., Simon R. Carding, Rhodes, Katherine A, Carding, Simon R., Elizabeth M. Andrew, Darren J. Newton, Carding, Simon R, Daniela Tramonti   +14 more
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The role of Fcgamma receptor III (CD16) in the regulation of gammadelta T cells in multiple sclerosis

, 2009
Multiple Sclerosis (MS) is an autoimmune central nervous system (CNS) disease characterized by inflammatory infiltrates alongside demyelinated axons, axonal transections and degenerating neurons; the exact mechanism whereby the immune system causes ...
Chen, Zhihong
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Gammadelta T Cells in Autoinflammatory Diseases

Autoinflammatory diseases are characterized by inappropriate activation of innate immunity resulting in excessive or persistent inflammation in the absence of infection. γδ T cells possess innate-like properties, including rapid responsiveness to stress-induced self-molecules, phosphoantigens, and inflammasome-derived cytokines, while retaining ...
openaire   +1 more source

T cell fate specification and alphabeta/gammadelta lineage commitment.

, 2001
The development of T cells from pluripotent stem cells involves a coordinated series of lineage-commitment steps. Common lymphoid precursors in the fetal liver or adult bone marrow must first choose between a T, B or NK cell fate.
Radtke, F., Wilson, A., MacDonald, H.R.
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Endotoxin induced chorioamnionitis results in migration of gammadelta T-cells to sites of mucosal damage at late GA.

, 2013
After 2d or 14d of endotoxin exposure, hardly any gammadelta T-cells were detected in the upper mucosa of the preterm intestine (A+B). At 140d GA, gammadelta T-cells were not detected in the lamina propria whereas lymphoid follicles in the basal mucosa ...
Rob M. J. Moonen (364538), Boris W. Kramer (110855), Yves Garnier (372377), Joep P. M. Derikx (370531), Tim G. A. M. Wolfs (320769), Luc J. I. Zimmermann (304180), Markus Gantert (372376), Geertje Thuijls (372375), Bea Zoer (372374), Eduardo Villamor (104711), Wim A. Buurman (162734)   +10 more
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The generation, immortalisation, and characterisation of human gammadelta T cells derived from the blood and cerebrospinal fluid of MS patients.

, 2001
Multiple sclerosis (MS) is believed to be an autoimmune, inflammatory, demyelinating disease of the central nervous system (CNS), resulting in myelin degradation, loss of the myelin forming cell, the oligodendrocyte (ODC), and axonal degeneration.
Pon, Robert A.
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Distinct subpopulations of gamma delta T cells are present in normal and tumor-bearing human liver

, 2004
gammadelta cells are thought to mediate immune responses at epithelial surfaces. We have quantified and characterized hepatic and peripheral blood gammadelta T cells from 11 normal and 13 unresolved tumor-bearing human liver specimens. gammadelta T cells
Norris, Suzanne, Kenna, T, Golden-Mason, Lucy, Tony Kenna, O'Farrelly, C, Norris, S, Hegarty, JE, John E. Hegarty, Suzanne Norris, Doherty, DG, Derek G. Doherty, Cliona O'Farrelly, O'Farrelly, Cliona, Golden-Mason, L, Hegarty, John E., Lucy Golden-Mason, Kenna, Tony, Doherty, Derek G.   +17 more
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Notch activity influences the alphabeta versus gammadelta T cell lineage decision.

, 1997
The choice between the alphabeta or gammadelta T cell fates is influenced by the production of functional, in-frame rearrangements of the TCR genes, but the mechanism that controls the lineage choice is not known.
Chang, D, Gridley, T, Washburn, T, Fowlkes, B J, Cado, D, Schweighoffer, E, Robey, E   +6 more
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TCR-beta chains derived from peripheral gammadelta T cells can take part in alphabeta T-cell development

, 2008
Between 10 and 20% of the peripheral gammadelta T cells express cytoplasmic TCR-beta proteins, but whether such TCR-beta chains can partake in alphabeta T-cell development has never been systematically investigated. Therefore, we reconstituted the T-cell
Bosco, N., Rolink, J., Engdahl, C., Bénard, A., Rolink, A. G., Ceredig, R.   +5 more
core  

"Corrigendum: Ontogeny of innate T lymphocytes – some innate lymphocytes are more innate than others"

Frontiers in Immunology, 2015
David eVermijlen, Immo ePrinz
doaj   +1 more source