Role of Natural Killer and Gamma-Delta T cells in West Nile Virus Infection
Viruses, 2013 Natural Killer (NK) cells and Gamma-delta T cells are both innate lymphocytes that respond rapidly and non-specifically to viral infection and other pathogens. They are also known to form a unique link between innate and adaptive immunity.
Thomas Welte, Tian Wang
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Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis [PDF]
, 2014 Parasitic worms are able to survive in their mammalian host for many years due to their ability to manipulate the immune response by secreting immunomodulatory products. It is increasingly clear that, reflecting the anti-inflammatory actions of such worm-
Al-Riyami, L. +3 more
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Cell Reports, 2019 Summary: Inflammatory bowel disease (IBD) is a complex autoimmune disorder recently shown to be associated with SUMOylation, a post-translational modification mechanism.
Aamir Suhail +8 more
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RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients [PDF]
, 2019 Dysregulated IL-23/IL-17 responses have been linked to psoriatic arthritis and other forms of spondyloarthritides (SpA). ROR gamma t, the key Thelperl7 (Th17) cell transcriptional regulator, is also expressed by subsets of innate-like T cells, including ...
Coudenys, Julie +27 more
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Cancer Communications, Volume 44, Issue 3, Page 448-452, March 2024.
Donghai Xiong +7 more
wiley +1 more source
Frontiers in ImmunologyOvarian carcinomas have the highest lethality amongst gynecological tumors. A problem after primary resection is the recurrence of epithelial ovarian carcinomas which is often associated with chemotherapy resistance.
Jan Schadeck +7 more
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Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]
, 2017 Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Aya Castañeda, Maria del Rosario +6 more
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Innate-like T cells in children with sickle cell disease.
PLoS ONE, 2019 BACKGROUND:The implication of lymphocytes in sickle cell disease pathogenesis is supported by a number of recent reports. These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not ...
Slimane Allali +8 more
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Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis. [PDF]
, 2018 There is a need for treatments that can safely promote regulatory lymphocyte responses. T cells express GABA receptors (GABAA-Rs) and GABA administration can inhibit Th1-mediated processes such as type 1 diabetes and rheumatoid arthritis in mouse models.
Dang, Hoa +4 more
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Comparison of porcine CD4 and gamma-delta T cell systemic and mucosal responses to the spirochete Brachyspira hyodysenteriae [PDF]
, 2002 In pigs, alphabeta CD4+ and gammadelta T cells constitute an important fraction of the circulating lymphocyte pool. This makes porcine an ideal animal model for functional studies of the two cell populations.
Hontecillas-Magarzo, Raquel
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