Results 81 to 90 of about 8,798 (217)

γδ T LYMPHOCYTES AS A FIRST LINE OF IMMUNE DEFENSE: OLD AND NEW WAYS OF ANTIGEN RECOGNITION AND IMPLICATIONS FOR CANCER IMMUNOTHERAPY.

Frontiers in Immunology, 2014
Among γδT cells, the Vδ1 subset, resident in epithelial tissues, is implied in the defense against viruses, fungi and certain hematological malignancies, while the circulating Vδ2 subpopulation mainly respond to mycobacteria and solid tumors.
Maria Raffaella eZocchi, Alessandro ePoggi   +1 more
doaj   +1 more source

Function and Spatial Organization of Tumor‐Invasive Human γδ T Cells—What Do We Know?

European Journal of Immunology, Volume 55, Issue 1, January 2025.
This review provides deeper insights into the localization of intra‐tumoral γδ T lymphocytes in solid tumors. Additionally, a pro‐ or anti‐tumoral influence of the tumor microenvironment and expression of checkpoint inhibitory molecules on γδ T cell functionality is described.
Kilian Wistuba‐Hamprecht, Hans‐Heinrich Oberg, Daniela Wesch   +2 more
wiley   +1 more source

UEG Week 2022 Poster Presentations

, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 473-1092, October 2022.
wiley   +1 more source

SOX‐5 Transcription Factor: a Novel Psoriatic Autoantigen Preferentially Found in Women

ACR Open Rheumatology, Volume 6, Issue 12, Page 807-819, December 2024.
Objective Adaptive immunity mediates psoriatic disease pathogenesis. We aimed to identify novel psoriatic autoantigens and their phenotypic associations in deeply characterized patient cohorts. Methods Sera from psoriatic arthritis (PsA) patients were used for autoantibody discovery.
Ana‐Maria Orbai, David Fiorentino, Jamie Perin, Erika Darrah, Qingyuan Yang, Laura Gutierrez‐Alamillo, Clifton O. Bingham, Michelle Petri, Antony Rosen, Livia Casciola‐Rosen   +9 more
wiley   +1 more source

Correction to: Gamma-delta (γδ) T cells: friend or foe in cancer development?

Journal of Translational Medicine, 2018
Following publication of the original article [1], the authors reported that they omitted to state that parts of Fig. 2 were adapted from Van Acker et al. [2] published by Taylor & Francis Ltd (www.tandfonline.com).
Yijing Zhao, Chao Niu, Jiuwei Cui
doaj   +1 more source

Hepatosplenic gammadelta T-cell lymphoma.

World journal of gastroenterology, 2005
To investigate the clinicopathologic characteristics, immunophenotype and TCR gene rearrangements of hepatosplenic T-cell lymphoma in eight Chinese patients.Eight Chinese patients with hepatosplenic gammadelta T-cell lymphomas were studied. Hematoxylin-eosin-stained slides and clinical histories were reviewed.
Shuan-Zeng, Wei, Tong-Hua, Liu, De-Tian, Wang, Jin-Ling, Cao, Yu-Feng, Luo, Zhi-Yong, Liang   +5 more
openaire   +1 more source

Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia

BMC Immunology, 2012
Background Staphylococcus aureus is the major cause of hospital-acquired and community-acquired pneumonia. Host defense to S.aureus infection is largely mediated by the innate immune system.
Cheng Ping, Liu Tao, Zhou Wei-Ying, Zhuang Yuan, Peng Liu-sheng, Zhang Jin-yu, Yin Zhi-Nan, Mao Xu-hu, Guo Gang, Shi Yun, Zou Quan-ming   +10 more
doaj   +1 more source

Tumor-Infiltrating γδ T Cells Suppress T and Dendritic Cell Function via Mechanisms Controlled by a Unique Toll-like Receptor Signaling Pathway [PDF]

, 2007
Summaryγδ T cells are important contributors to innate immunity against cancer, but their regulatory role in controlling immune responses remains largely unknown.
Guangyong Peng, Helen Y. Wang, Weiyi Peng, Yukiko Kiniwa, Kook Heon Seo, Rong-Fu Wang, Akira, Bauer, Boismenu, Brenner, Bukowski, Choudhary, Constant, Crellin, Curiel, Diefenbach, Dunn, Eberl, Girardi, Groh, Groh, Havran, Hayday, Hayday, Huang, Huang, Jameson, Jameson, Jurk, Kabelitz, Liu, Liyanage, Modlin, Okita, Pasare, Peng, Pennington, Pennington, Qin, Rosenberg, Sakaguchi, Sato, Sato, Shevach, Shin, Sutmuller, Sutmuller, Wan, Wang, Wang, Wang, Wang, Wang, Woo   +53 more
core   +6 more sources

Benefit of axicabtagene ciloleucel versus chemoimmunotherapy in older patients and/or patients with poor ECOG performance status with relapsed or refractory large B‐cell lymphoma after 2 or more lines of prior therapy

American Journal of Hematology, Volume 99, Issue 5, Page 880-889, May 2024.
Abstract Axicabtagene ciloleucel (axi‐cel) in trials has demonstrated favorable efficacy compared with historical controls after ≥2 lines of therapy for the treatment of relapsed or refractory (R/R) large B cell lymphoma (LBCL). Herein, we compared the real‐world effectiveness of axi‐cel with efficacy and effectiveness of chemoimmunotherapy (CIT) in ...
Matthew A. Lunning, Hai‐lin Wang, Zhen‐Huan Hu, Frederick L. Locke, Tanya Siddiqi, Caron A. Jacobson, Sairah Ahmed, David B. Miklos, Yi Lin, Brian T. Hill, Armin Ghobadi, Sattva S. Neelapu, Jason Westin, Christopher Dieyi, Polly Field, Harry Miao, Shilpa A. Shahani, Anik Patel, Clare Spooner, Christine Fu, David Muramoto, Hairong Xu, Marcelo C. Pasquini   +22 more
wiley   +1 more source

Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance

Microbiome, 2023
Background Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition.
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, Chantal Kuhn, Howard L. Weiner   +16 more
doaj   +1 more source