Results 81 to 90 of about 13,834,757 (208)

Potential Roles of Gamma-Delta T Cells in a Bacterial Immun-Ization Model

Vaccines
Background/Objective: Francisella tularensis is a highly infectious intracellular pathogen that causes severe pulmonary tularemia following aerosol exposure, yet no licensed vaccine exists.
Lee Anne Talbot, Raffi Manjikian, Constantine Bitsaktsis   +2 more
doaj   +1 more source

DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

Cell Reports, 2019
Summary: Inflammatory bowel disease (IBD) is a complex autoimmune disorder recently shown to be associated with SUMOylation, a post-translational modification mechanism.
Aamir Suhail, Zaigham Abbas Rizvi, Prabhakar Mujagond, Syed Azmal Ali, Preksha Gaur, Mukesh Singh, Vineet Ahuja, Amit Awasthi, Chittur Venkateshwaran Srikanth   +8 more
doaj   +1 more source

Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillance

, 2006
Normal (noninflamed) human skin contains a network of lymphocytes, but little is known about the homing and function of these cells. The majority of αβ T cells in normal skin express CCR8 and produce proinflammatory cytokines.
Meuter, Simone, Meuter, S., Moser, Bernhard, Ebert, L. M., Ebert, Lisa   +4 more
core   +1 more source

Innate-like T cells in children with sickle cell disease.

PLoS ONE, 2019
BACKGROUND:The implication of lymphocytes in sickle cell disease pathogenesis is supported by a number of recent reports. These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not ...
Slimane Allali, Céline Dietrich, François Machavoine, Rachel Rignault-Bricard, Valentine Brousse, Mariane de Montalembert, Olivier Hermine, Thiago Trovati Maciel, Maria Leite-de-Moraes   +8 more
doaj   +1 more source

Bovine gammadelta T Cells Are a Major Regulatory T Cell Subset

, 2014
In humans and mice, γδ T cells represent <5% of the total circulating lymphocytes. In contrast, the γδ T cell compartment in ruminants accounts for 15-60% of the total circulating mononuclear lymphocytes. Despite the existence of CD4(+)CD25(high) Foxp3(+) T cells in the bovine system, these are neither anergic nor suppressive.
Guzman, Efrain, Hope, Jayne; id_orcid 0000-0001-6573-6172, Taylor, Geraldine, Smith, Adrian L, Cubillos-Zapata, Carolina, Charleston, Bryan   +5 more
openaire   +1 more source

Diversity of gammadelta T cells in patients with Behcet's disease is indicative of polyclonal activation

, 2006
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldOBJECTIVE: Behcet's disease (BD) is a multisystemic disease, with vasculitic lesions in the oral and genital mucosa, eyes, joints, skin and ...
Farmer, I, F Fortune, Lau, S-H, J Freysdottir, Freysdottir, J, I Farmer, S‐H Lau, Fortune, F, Hussain, L, L Hussain   +9 more
core   +1 more source

Human cytomegalovirus elicits fetal gammadelta T cell responses in utero.

, 2010
The fetus and infant are highly susceptible to viral infections. Several viruses, including human cytomegalovirus (CMV), cause more severe disease in early life compared with later life. It is generally accepted that this is a result of the immaturity of
Willems, Fabienne, Catherine Donner, Michel Van Rysselberge, Twite, Nicolas, donner, catherine, Tackoen, Marie, Arnaud Marchant, Brouwer, Margreet, Michel Goldman, Vermijlen, David, Corinne Liesnard, Fabienne Willems, Nicolas Twité, Goldman, Michel, Margreet Brouwer, David Vermijlen, Marie Tackoen, Liesnard, Corinne, Marchant, Arnaud, Van Rysselberge, Michel   +19 more
core   +1 more source

Phenotypic characterization of gammadelta T cells mobilized in response to acute psychological stress.

, 2010
Gamma Delta (gammadelta) T lymphocytes are versatile cells that play key roles in a number of functions, including bacterial clearance, wound repair, and delayed-type hypersensitivity reactions.
Bosch, Jos, Kate M. Edwards, Jos A. Bosch, Victoria E. Burns, Edwards, KM, Veldhuijzen van Zanten, Joachimina; id_orcid, Leila H. Anane, Jet J.C.S. Veldhuijzen van Zanten, Anane, Leila, Burns, Victoria; id_orcid, Mark T. Drayson, Drayson, Mark   +11 more
core   +1 more source

Identification of novel gammadelta T-cell subsets following bacterial infection in the absence of Vgamma1+ T cells:homeostatic control of gammadelta T-cell responses to pathogen infection by Vgamma1+ T cells

, 2006
Although gammadelta T cells are a common feature of many pathogen-induced immune responses, the factors that influence, promote, or regulate the response of individual gammadelta T-cell subsets to infection is unknown. Here we show that in the absence of
Dalton, Jane E., Dalton, Jane E, Newton, Darren J, Newton, Darren J., Jane E. Dalton, Andrew, Elizabeth M, Rainy Mears, Andrew, Elizabeth M., Simon R. Carding, Carding, Simon R., Elizabeth M. Andrew, Mears, Rainy, Darren J. Newton, Carding, Simon R   +13 more
core   +1 more source

UEG Week 2024 Oral Presentations

United European Gastroenterology Journal, Volume 12, Issue S8, Page 9-200, October 2024.
wiley   +1 more source