Results 61 to 70 of about 13,834,757 (208)

γδ T LYMPHOCYTES AS A FIRST LINE OF IMMUNE DEFENSE: OLD AND NEW WAYS OF ANTIGEN RECOGNITION AND IMPLICATIONS FOR CANCER IMMUNOTHERAPY.

Frontiers in Immunology, 2014
Among γδT cells, the Vδ1 subset, resident in epithelial tissues, is implied in the defense against viruses, fungi and certain hematological malignancies, while the circulating Vδ2 subpopulation mainly respond to mycobacteria and solid tumors.
Maria Raffaella eZocchi, Alessandro ePoggi   +1 more
doaj   +1 more source

Effector gammadelta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma

, 2005
The aim of this study was to investigate the in vitro immunomodulatory effects of zoledronic acid (Zol) on peripheral blood Vitalic gamma9/Vdelta2 (italic gammadelta) T cells of normal donors and multiple myeloma (MM) patients.
COSCIA, Marta, CASTELLA, BARBARA, PALUMBO, Antonio, Muraro M, FOGLIETTA, MYRIAM, Boano L, BRUNO, Benedetto, Bertieri R, Pantaleoni F, Fiore F, MASSAIA, Massimo, Peola S, BOCCADORO, Mario, MARIANI, Sara, Nuschak B   +14 more
core   +1 more source

The expression of TCR-gamma delta/CD3 complex in neoplastic gamma delta T-cell

Haematologica, 2006
We describe that the neoplastic gammadelta T-cells from patients with hepatosplenic gammadelta T-cell lymphoma have a lower expression of TCR-gammadelta/CD3 complex compared to their normal or reactive counterparts.
L Baseggio, F Berger, G Monneret, JP Magaud, G Salles, P Felman   +5 more
doaj  

Benefit of axicabtagene ciloleucel versus chemoimmunotherapy in older patients and/or patients with poor ECOG performance status with relapsed or refractory large B‐cell lymphoma after 2 or more lines of prior therapy

American Journal of Hematology, Volume 99, Issue 5, Page 880-889, May 2024.
Abstract Axicabtagene ciloleucel (axi‐cel) in trials has demonstrated favorable efficacy compared with historical controls after ≥2 lines of therapy for the treatment of relapsed or refractory (R/R) large B cell lymphoma (LBCL). Herein, we compared the real‐world effectiveness of axi‐cel with efficacy and effectiveness of chemoimmunotherapy (CIT) in ...
Matthew A. Lunning, Hai‐lin Wang, Zhen‐Huan Hu, Frederick L. Locke, Tanya Siddiqi, Caron A. Jacobson, Sairah Ahmed, David B. Miklos, Yi Lin, Brian T. Hill, Armin Ghobadi, Sattva S. Neelapu, Jason Westin, Christopher Dieyi, Polly Field, Harry Miao, Shilpa A. Shahani, Anik Patel, Clare Spooner, Christine Fu, David Muramoto, Hairong Xu, Marcelo C. Pasquini   +22 more
wiley   +1 more source

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]

, 2010
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H, Dzhambazov, Balik, Bockermann, Robert, Bettina Sehnert, Batsalova, Tsvetelina, Harald Burkhardt, Burkhardt, Harald, Robert Bockermann, Baecklund, Johan, Batsalova, T, Bockermann, R, Dzhambazov, B, Merky, Patrick, Baecklund, J, Bäcklund, Johan, Sehnert, B, Patrick Merky, Sehnert, Bettina, Balik Dzhambazov, Tsvetelina Batsalova, Lund University., Johan Backlund, Merky, P,, Bockermann, Robert,   +23 more
core   +1 more source

Pentostatin (2'-deoxycoformycin) for the treatment of hepatosplenic gammadelta T-cell lymphomas

Haematologica, 2005
We report the results of treatment with single agent 2'-deoxycoformycin (Pentostatin) in two patients with Hepatosplenic gammadelta T-cell lymphoma (HSgammadeltaTCL), a rare lymphoma subtype with a highly unfavorable prognosis.
G Corazzelli, G Capobianco, F Russo, F Frigeri, D Aldinucci, A Pinto   +5 more
doaj  

Correction to: Gamma-delta (γδ) T cells: friend or foe in cancer development?

Journal of Translational Medicine, 2018
Following publication of the original article [1], the authors reported that they omitted to state that parts of Fig. 2 were adapted from Van Acker et al. [2] published by Taylor & Francis Ltd (www.tandfonline.com).
Yijing Zhao, Chao Niu, Jiuwei Cui
doaj   +1 more source

Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]

, 2009
Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
Hao He, Lin, X.M., Peizeng Yang, Jiang, L.Q., Hongyan Zhou, Aize Kijlstra, Liqiong Jiang, Huang, X.K., Yang, P.Z., He, H., Zhou, H.Y., Xiaomin Lin, Xiangkun Huang, Kijlstra, A.   +13 more
core   +1 more source

Late Epstein-Barr virus infection of a hepatosplenic gamma delta T-cell lymphoma arising in a kidney transplant recipient

Haematologica, 2000
BACKGROUND AND OBJECTIVE: gd T-cell lymphomas are only exceptionally observed in transplanted patients. Aim of this study was the detailed characterization of one such case.
S Roncella, G Cutrona, M Truini, I Airoldi, A Pezzolo, A Valetto, D Di Martino, P Dadati, A De Rossi, M Ulivi, I Fontana, A Nocera, U Valente, M Ferrarini, V Pistoia   +14 more
doaj  

Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia

BMC Immunology, 2012
Background Staphylococcus aureus is the major cause of hospital-acquired and community-acquired pneumonia. Host defense to S.aureus infection is largely mediated by the innate immune system.
Cheng Ping, Liu Tao, Zhou Wei-Ying, Zhuang Yuan, Peng Liu-sheng, Zhang Jin-yu, Yin Zhi-Nan, Mao Xu-hu, Guo Gang, Shi Yun, Zou Quan-ming   +10 more
doaj   +1 more source