Results 61 to 70 of about 2,337 (177)

The Unknown Unknowns: Recovering Gamma-Delta T Cells for Control of Human Immunodeficiency Virus (HIV)

Viruses, 2020
Recent advances in γδ T cell biology have focused on the unique attributes of these cells and their role in regulating innate and adaptive immunity, promoting tissue homeostasis, and providing resistance to various disorders. Numerous bacterial and viral
Shivkumar Biradar, Michael T. Lotze, Robbie B. Mailliard   +2 more
doaj   +1 more source

Role of Natural Killer and Gamma-Delta T cells in West Nile Virus Infection

Viruses, 2013
Natural Killer (NK) cells and Gamma-delta T cells are both innate lymphocytes that respond rapidly and non-specifically to viral infection and other pathogens. They are also known to form a unique link between innate and adaptive immunity.
Thomas Welte, Tian Wang
doaj   +1 more source

Vdelta1 T cells are more resistant than Vdelta2 T cells to the immunosuppressive properties of galectin-3

Frontiers in Immunology
Ovarian carcinomas have the highest lethality amongst gynecological tumors. A problem after primary resection is the recurrence of epithelial ovarian carcinomas which is often associated with chemotherapy resistance.
Jan Schadeck, Hans-Heinrich Oberg, Matthias Peipp, Nina Hedemann, Wolfgang W. Schamel, Wolfgang W. Schamel, Dirk Bauerschlag, Daniela Wesch   +7 more
doaj   +1 more source

Innate-like T cells in children with sickle cell disease.

PLoS ONE, 2019
BACKGROUND:The implication of lymphocytes in sickle cell disease pathogenesis is supported by a number of recent reports. These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not ...
Slimane Allali, Céline Dietrich, François Machavoine, Rachel Rignault-Bricard, Valentine Brousse, Mariane de Montalembert, Olivier Hermine, Thiago Trovati Maciel, Maria Leite-de-Moraes   +8 more
doaj   +1 more source

Hepatosplenic gammadelta T-cell lymphoma.

World journal of gastroenterology, 2005
To investigate the clinicopathologic characteristics, immunophenotype and TCR gene rearrangements of hepatosplenic T-cell lymphoma in eight Chinese patients.Eight Chinese patients with hepatosplenic gammadelta T-cell lymphomas were studied. Hematoxylin-eosin-stained slides and clinical histories were reviewed.
Shuan-Zeng, Wei, Tong-Hua, Liu, De-Tian, Wang, Jin-Ling, Cao, Yu-Feng, Luo, Zhi-Yong, Liang   +5 more
openaire   +1 more source

Mitochondria‐targeted atovaquone promotes anti‐lung cancer immunity by reshaping tumor microenvironment and enhancing energy metabolism of anti‐tumor immune cells

Cancer Communications, Volume 44, Issue 3, Page 448-452, March 2024.
Donghai Xiong, Zheng Yin, Mofei Huang, Yian Wang, Micael Hardy, Balaraman Kalyanaraman, Stephen T Wong, Ming You   +7 more
wiley   +1 more source

Potential Roles of Gamma-Delta T Cells in a Bacterial Immun-Ization Model

Vaccines
Background/Objective: Francisella tularensis is a highly infectious intracellular pathogen that causes severe pulmonary tularemia following aerosol exposure, yet no licensed vaccine exists.
Lee Anne Talbot, Raffi Manjikian, Constantine Bitsaktsis   +2 more
doaj   +1 more source

DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

Cell Reports, 2019
Summary: Inflammatory bowel disease (IBD) is a complex autoimmune disorder recently shown to be associated with SUMOylation, a post-translational modification mechanism.
Aamir Suhail, Zaigham Abbas Rizvi, Prabhakar Mujagond, Syed Azmal Ali, Preksha Gaur, Mukesh Singh, Vineet Ahuja, Amit Awasthi, Chittur Venkateshwaran Srikanth   +8 more
doaj   +1 more source

Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.

PLoS ONE, 2009
BackgroundThiazolidinediones (TZD) class of drugs, and 15-deoxy-D12,14-prostaglandin J2 (15d-PGJ2) are immune regulators predicted to modulate human autoimmune disease. Their effects on gammadelta T cells, which are involved in animal model and human and
Haishan Li, C David Pauza
doaj   +1 more source

Bovine gammadelta T Cells Are a Major Regulatory T Cell Subset

, 2014
In humans and mice, γδ T cells represent <5% of the total circulating lymphocytes. In contrast, the γδ T cell compartment in ruminants accounts for 15-60% of the total circulating mononuclear lymphocytes. Despite the existence of CD4(+)CD25(high) Foxp3(+) T cells in the bovine system, these are neither anergic nor suppressive.
Guzman, Efrain, Hope, Jayne; id_orcid 0000-0001-6573-6172, Taylor, Geraldine, Smith, Adrian L, Cubillos-Zapata, Carolina, Charleston, Bryan   +5 more
openaire   +1 more source