Results 41 to 50 of about 14,828,306 (213)
γδ T Cells in Emerging Viral Infection: An Overview
Viruses, 2022 New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern.
Eleonora Cimini, Chiara Agrati
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Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, Volume 45, Issue 8, Page 888-913, August 2025.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
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HemaSphere, Volume 9, Issue 8, August 2025.Abstract Gamma delta (γδ) T cells, which constitute about 5%–10% of peripheral blood lymphocytes, play key roles in tumor immunosurveillance and are often enriched within epithelial tissues. They are unique in their Major Histocompatibility Complex‐independent antigen recognition via the γδ T‐cell receptor (TCR) as well as via innate receptors, making ...
Charles Agbuduwe +2 more
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PLoS Pathogens, 2010 Differentiation, distribution and immune regulation of human IL-22-producing T cells in infections remain unknown. Here, we demonstrated in a nonhuman primate model that M.
Shuyu Yao +6 more
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Ontogeny of innate T lymphocytes - some innate lymphocytes are more innate then others
Frontiers in Immunology, 2014 Innate lymphocytes have recently received a lot of attention. However, there are different ideas about the definition of what is innate in lymphocytes. Lymphocytes without V(D)J-rearranged antigen receptors are now termed innate lymphoid cells (ILCs) and
David eVermijlen, Immo ePrinz
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Frontiers in Immunology, 2020 Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism for ...
Daniel Gonnermann +7 more
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Stimulatory and inhibitory activity of STING ligands on tumor-reactive human gamma/delta T cells
OncoImmunology, 2022 Ligands for Stimulator of Interferon Genes (STING) receptor are under investigation as adjuvants in cancer therapy. Multiple effects have been described, including induction of immunogenic cell death and enhancement of CD8 T-cell mediated anti-tumor ...
Ruben Serrano +5 more
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Gamma-delta (γδ) T cells: friend or foe in cancer development?
Journal of Translational Medicine, 2018 Background γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains with diverse structural and functional heterogeneity.
Yijing Zhao, Chao Niu, Jiuwei Cui
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Characterization of human infiltrating and circulating gamma-delta T cells in prostate cancer [PDF]
Investigative and Clinical Urology, 2019 Purpose: The aim of our study was to prospectively evaluate the distribution of gamma-delta (γδ)1 and γδ2 T cells and their phenotypes in peripheral blood and prostate samples of patients diagnosed with or without prostate cancer (PCa) at prostate biopsy.
Marco Vella +7 more
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Hematological Oncology, Volume 43, Issue 3, May 2025.ABSTRACT To better understand the comparative effectiveness of axicabtagene ciloleucel (axi‐cel) to historical standard of care (SoC) for the treatment of refractory diffused large B‐cell lymphoma (DLBCL) among patients of Asian descent, we conducted a matching‐adjusted indirect treatment comparison (MAIC) of the pivotal ZUMA‐1 trial (NCT02348216) and ...
Frederick L. Locke +6 more
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