Results 41 to 50 of about 13,834,757 (208)

γδ T Cells in Emerging Viral Infection: An Overview

open access: yesViruses, 2022
New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern.
Eleonora Cimini, Chiara Agrati
doaj   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

open access: yesCancer Communications, Volume 45, Issue 8, Page 888-913, August 2025.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai   +6 more
wiley   +1 more source

Immuneregulatory functions of gammadelta T Lyphocytes [PDF]

open access: yes, 2013
Im Rahmen dieser Arbeit konnte die Suppression der Proliferation von CD4+CD25- (Responder) T-Zellen durch frisch isolierte gammadelta T-Zellen gezeigt werden.
Peters, Christian
core   +1 more source

Harnessing the immunotherapeutic potentials of gamma delta T cells against hematological malignancies

open access: yesHemaSphere, Volume 9, Issue 8, August 2025.
Abstract Gamma delta (γδ) T cells, which constitute about 5%–10% of peripheral blood lymphocytes, play key roles in tumor immunosurveillance and are often enriched within epithelial tissues. They are unique in their Major Histocompatibility Complex‐independent antigen recognition via the γδ T‐cell receptor (TCR) as well as via innate receptors, making ...
Charles Agbuduwe   +2 more
wiley   +1 more source

Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis.

open access: yesPLoS Pathogens, 2010
Differentiation, distribution and immune regulation of human IL-22-producing T cells in infections remain unknown. Here, we demonstrated in a nonhuman primate model that M.
Shuyu Yao   +6 more
doaj   +1 more source

Ontogeny of innate T lymphocytes - some innate lymphocytes are more innate then others

open access: yesFrontiers in Immunology, 2014
Innate lymphocytes have recently received a lot of attention. However, there are different ideas about the definition of what is innate in lymphocytes. Lymphocytes without V(D)J-rearranged antigen receptors are now termed innate lymphoid cells (ILCs) and
David eVermijlen, Immo ePrinz
doaj   +1 more source

Galectin-3 Released by Pancreatic Ductal Adenocarcinoma Suppresses γδ T Cell Proliferation but Not Their Cytotoxicity

open access: yesFrontiers in Immunology, 2020
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism for ...
Daniel Gonnermann   +7 more
doaj   +1 more source

Characterization of human infiltrating and circulating gamma-delta T cells in prostate cancer [PDF]

open access: yesInvestigative and Clinical Urology, 2019
Purpose: The aim of our study was to prospectively evaluate the distribution of gamma-delta (γδ)1 and γδ2 T cells and their phenotypes in peripheral blood and prostate samples of patients diagnosed with or without prostate cancer (PCa) at prostate biopsy.
Marco Vella   +7 more
doaj   +1 more source

Gamma-delta (γδ) T cells: friend or foe in cancer development?

open access: yesJournal of Translational Medicine, 2018
Background γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains with diverse structural and functional heterogeneity.
Yijing Zhao, Chao Niu, Jiuwei Cui
doaj   +1 more source

Differential Skewing of Circulating MR1-Restricted and γδ T Cells in Human Psoriasis Vulgaris

open access: yesFrontiers in Immunology, 2020
Psoriasis vulgaris (PV) is a chronic, recurrent inflammatory dermatosis mediated by aberrantly activated immune cells. The role of the innate-like T cells, particularly gammadelta T (γδT) cells and MR1-restricted T lymphocytes, is incompletely explored ...
Vera Plužarić   +11 more
doaj   +1 more source

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