BackgroundId3 is a dominant antagonist of E protein transcription factor activity that is induced by signals emanating from the alphabeta and gammadelta T cell receptor (TCR).
Mihalis Verykokakis +5 more
doaj +1 more source
Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas. [PDF]
Primary cutaneous CD8-positive aggressive epidermotropic T-cell lymphoma is a rare and poorly characterized variant of cutaneous lymphoma still considered a provisional entity in the latest 2016 World Health Organization Classification of Cutaneous ...
Duvic, Madeleine +19 more
core +1 more source
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure. [PDF]
Vδ2+ γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection in naïve adults, but are lost and become dysfunctional among children repeatedly exposed to malaria.
Bowen, Katherine +17 more
core +2 more sources
Crosstalk between innate and adaptive pathways is a critical component to developing an effective, lasting immune response. Among natural effector cells, innate-like γδ T cells promote immunity by facilitating communication between the two compartments ...
Matthew L. Clohosey +6 more
doaj +1 more source
Chemotherapy accelerates immune-senescence and functional impairments of Vδ2pos T cells in elderly patients affected by liver metastatic colorectal cancer. [PDF]
Human (gamma delta) γδ T cells are unconventional innate-like lymphocytes displaying a broad array of anti-tumor activities with promising perspectives in cancer immunotherapy.
Bruni E +9 more
core +1 more source
Human γδ T-Cell Control of Mucosal Immunity and Inflammation
Human γδ T-cells include some of the most common “antigen-specific” cell types in peripheral blood and are enriched yet further at mucosal barrier sites where microbial infection and tumors often originate.
Neil E. McCarthy, Matthias Eberl
doaj +1 more source
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. [PDF]
The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and infected cells and facilitate immune rejection of tumor cells.
Hsiung, Benjamin +4 more
core +2 more sources
Transverse myelitis after anti‐CD19 directed CAR T cell therapy for relapsed large B cell lymphoma
eJHaem, Volume 3, Issue 1, Page 223-227, February 2022.
Semira Sheikh +10 more
wiley +1 more source
TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele +11 more
core +1 more source
Gamma/Delta T Cells and Their Role in Protection Against Malaria
Whether and how γδT cells play a protective role in immunity against Plasmodium infection remain open questions. γδT cells expand in patients and mice infected with Plasmodium spp, and cytokine production and cytotoxic responses against blood-stage ...
Katrien Deroost, Jean Langhorne
doaj +1 more source

