Results 121 to 130 of about 2,337 (177)

Murine T cell determination of pregnancy outcome: I. Effects of strain, alphabeta T cell receptor, gammadelta T cell receptor, and gammadelta T cell subsets.

American journal of reproductive immunology (New York, N.Y. : 1989), 1997
T cells bearing alphabeta T cell receptor (TcR) and gammadelta TcR are present at the fetomaternal interface, and the latter, which express surface activation markers, can react with fetal trophoblast cell antigens. What is the role of these cells?Using stress-abortion-prone DBA/2-mated CBA/J and abortion-resistant C57/B16 mice, alphabeta, gammadelta ...
P C, Arck, D A, Ferrick, D, Steele-Norwood, K, Croitoru, D A, Clark   +4 more
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Gammadelta T cell receptors without a job.

Immunity, 2009
In this issue of Immunity, the studies by Sutton et al. (2009) and Martin et al. (2009) indicate that gammadelta T cells are innate cells that rapidly produce interleukin (IL)-17 in response to cytokines or pathogens without the need for T cell receptor engagement.
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Gammadelta T-cell precursor-derived CD4- CD8- alphabeta T cells retain gammadelta cell function.

Scandinavian journal of immunology, 1998
We have previously shown that some of the DN alphabeta+ T cells arising in TcR alpha-chain transgenic mice are of gammadelta T cell origin, based on phenotypic data and on their status of TcR gene rearrangements. In the present report we investigated the impact of alphabeta TcR expression on the functional programme of the mature gammadelta precursor ...
M, Fritsch, F, Ivars
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Development and selection of gammadelta T cells.

Immunological reviews, 2007
Two main lineages of T cells develop in the thymus: those that express the alphabeta T-cell receptor (TCR) and those that express the gammadelta TCR. Whereas the development, selection, and peripheral localization of newly differentiated alphabeta T cells are understood in some detail, these processes are less well characterized in gammadelta T cells ...
Na, Xiong, David H, Raulet
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Immunoregulation in the tissues by gammadelta T cells.

Nature reviews. Immunology, 2003
For a T-cell subset to be classified as immunoregulatory, it might reasonably be predicted that in its absence, animals would experience pathological immune dysregulation. Moreover, reconstitution of the subset should restore normal immune regulation.
Hayday, A, Tigelaar, R
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Heterogeneity of avian gammadelta T cells.

Veterinary immunology and immunopathology, 2008
gammadelta T cells are distinct with respect to tissue localisation, phenotype and biological functions and similarities between species are not very apparent. To elucidate local and functional heterogeneity of non-stimulated avian gammadelta T cells, the CD8-characterised gammadelta T cell subsets [CD8alpha(+high) (CD8alphaalpha(+) and CD8alphabeta(+))
Jana, Pieper, Ulrich, Methner, Angela, Berndt   +2 more
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Antiviral reactivities of gammadelta T cells.

Microbes and infection, 2005
The complex antiviral immune mechanisms involve both adaptive and innate reactions mediated by gammadelta T lymphocytes, whose unique immunosurveillance contributions are analyzed here in different clinical and experimental settings. It is beyond any doubt that the fast, potent, cytotoxic as well as non-cytolytic antiviral activities of gammadelta T ...
Fabrizio, Poccia, Chiara, Agrati, Federico, Martini, Maria Rosaria, Capobianchi, Marianne, Wallace, Miroslav, Malkovsky   +5 more
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Antigen recognition by gammadelta T cells.

Immunological reviews, 2007
gammadelta T cells contribute to host immune competence uniquely. This is most likely because they have distinctive antigen-recognition properties. While the basic organization of gammadelta T-cell receptor (TCR) loci is similar to that of alphabeta TCR loci, there is a striking difference in how the diversity of gammadelta TCRs is generated ...
Yueh-hsiu, Chien, Yves, Konigshofer
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Immunosurveillance and immunoregulation by gammadelta T cells.

The Journal of investigative dermatology, 2006
Whereas the vast majority of T cells express a T-cell receptor (TCR) composed of alphabeta heterodimers, a smaller population expresses a gammadelta TCR. In contrast to alphabeta T cells, gammadelta T cells show less TCR diversity, are particularly enriched at epithelial surfaces and appear to respond to self-molecules that signal potential danger or ...
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gammadelta T cells in malaria infections.

Parasitology today (Personal ed.), 2005
The association of a pronounced gammadelta T-cell response with Plasmodium infections is intriguing. The ability of parasite material to activate gammadelta T cells in vitro, and the localization of these cells in vivo in the red pulp of the spleen, suggests that these cells could play a role in the killing of bloodstage malaria parasites. However, the
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