Results 131 to 140 of about 2,337 (177)

gammadelta T cells: novel initiators of adaptive immunity.

Immunological reviews, 2007
In this review, we discuss the potential role of human gammadelta T cells in the control of adaptive immunity. Our latest findings emerged as a consequence of our working hypothesis, which predicts a close relationship between the migration control in leukocytes and their function in immune processes as diverse as hematopoiesis, initiation of adaptive ...
Moser, Bernhard, Eberl, M
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Gammadelta T cells: an alternative type of professional APC.

Trends in immunology, 2006
A subtype of activated human gammadelta T cells, termed Vdelta2+ T cells, has antigen-presentation features similar in potency and efficacy to those seen in dendritic cells. Comparable treatment of alphabeta T cells does not result in 'professional' antigen presenting cells (APCs). What is so special about Vdelta2+ T cells?
Moser, Bernhard, Brandes, Marlène
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Gammadelta T cells and Mycobacterium tuberculosis.

Microbes and infection, 2000
Since the first descriptions of mycobacterial reactivity for gammadelta T cells in 1989, studies of gammadelta T-cell responses to M. tuberculosis in humans and animal models have increased our understanding of the complex role(s) of this T-cell subset not only in the immune response to M.
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Gammadelta T cells present antigen to CD4+ alphabeta T cells.

Journal of leukocyte biology, 1998
Gammadelta and alphabeta TCR+ T cells share many properties and their interactions are likely to be coordinated and regulated. We provide evidence that cattle gammadelta T cells are able to present antigen to CD4+ T cells. To help elucidate their function gammadelta T cell lines were propagated for extensive characterization.
R A, Collins, D, Werling, S E, Duggan, A P, Bland, K R, Parsons, C J, Howard   +5 more
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Function of intestinal gammadelta T cells.

Immunologic research, 2000
Mucosal tissues including the intestine, lung, reproductive tract, and skin form the major interfaces between the outside and internal milieus. Facing the outside is an epithelial cell layer, the epithelium, built on a vascular connective surface. In addition to performing specialized functions, mucosal tissues are sites where immune, epithelial, and ...
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Generation of human gammadelta T-cell repertoires.

Critical reviews in immunology, 2000
The nature of how the human gammadelta T-cell repertoire is generated during normal development is poorly understood. Unlike TCR -alphabeta+ cells that are almost exclusively dependent upon the thymus for their development and maturation, gammadelta T cells can be generated in extrathymic sites.
L D, McVay, S R, Carding
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gammadelta T-cell receptors: functional correlations.

Immunological reviews, 2007
The gammadelta T-cell receptors (TCRs) are limited in their diversity, suggesting that their natural ligands may be few in number. Ligands for gammadeltaTCRs that have thus far been determined are predominantly of host rather than foreign origin. Correlations have been noted between the Vgamma and/or Vdelta genes a gammadelta T cell expresses and its ...
Rebecca L, O'Brien, Christina L, Roark, Niyun, Jin, M Kemal, Aydintug, Jena D, French, Jennifer L, Chain, J M, Wands, Molly, Johnston, Willi K, Born   +8 more
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Cutaneous biology of gammadelta T cells.

Advances in dermatology, 2004
The vast majority of serious noninfectious skin diseases are the result of inappropriate inflammatory responses (eg, atopic dermatitis, psoriasis) or neoplastic transformation (eg, squamous cell carcinoma, melanoma, cutaneous T-cell lymphoma). T cells are critical to both of these major disease categories, playing critical roles in driving or ...
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[A case of hepatosplenic gammadelta T cell lymphoma].

Zhongguo shi yan xue ye xue za zhi, 2008
Hepatosplenic gammadelta T cell lymphoma represents rare, often aggressive type of malignant peripheral T-cell lymphoma, which is characterized by expressing T-cell-associated markers CD2, CD3 and gammadelta T-cell receptor, and nonactivated cytotoxic cell phenotype (TIA-1+, granzyme B-).
Fu-Xu, Wang, Xue-Jun, Zhang, Zuo-Ren, Dong   +2 more
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Gammadelta T Cells: Unconventional T Cells Involved in IBD Pathogenesis

Digestive Diseases and Sciences, 2018
Ignacio, Catalan-Serra, Juan Carlos, Andreu-Ballester, Torunn, Bruland, Arne Kristian, Sandvik   +3 more
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