Results 151 to 160 of about 13,834,757 (208)
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American journal of reproductive immunology (New York, N.Y. : 1989), 1997
T cells bearing alphabeta T cell receptor (TcR) and gammadelta TcR are present at the fetomaternal interface, and the latter, which express surface activation markers, can react with fetal trophoblast cell antigens. What is the role of these cells?Using stress-abortion-prone DBA/2-mated CBA/J and abortion-resistant C57/B16 mice, alphabeta, gammadelta ...
P C, Arck +4 more
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T cells bearing alphabeta T cell receptor (TcR) and gammadelta TcR are present at the fetomaternal interface, and the latter, which express surface activation markers, can react with fetal trophoblast cell antigens. What is the role of these cells?Using stress-abortion-prone DBA/2-mated CBA/J and abortion-resistant C57/B16 mice, alphabeta, gammadelta ...
P C, Arck +4 more
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Seminars in hematology, 2004
T-cell lymphomas expressing the gammadelta T-cell receptor (TCR) are uncommon, although their frequency may be underestimated. They show a broad clinicopathological spectrum. Besides precursor T-cell lymphoblastic leukemia/lymphoma, various post-thymic gammadelta T-cell neoplasms have been recognized.
Philippe, Gaulard +2 more
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T-cell lymphomas expressing the gammadelta T-cell receptor (TCR) are uncommon, although their frequency may be underestimated. They show a broad clinicopathological spectrum. Besides precursor T-cell lymphoblastic leukemia/lymphoma, various post-thymic gammadelta T-cell neoplasms have been recognized.
Philippe, Gaulard +2 more
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Gammadelta T cell receptors without a job.
Immunity, 2009In this issue of Immunity, the studies by Sutton et al. (2009) and Martin et al. (2009) indicate that gammadelta T cells are innate cells that rapidly produce interleukin (IL)-17 in response to cytokines or pathogens without the need for T cell receptor engagement.
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Gammadelta T-cell precursor-derived CD4- CD8- alphabeta T cells retain gammadelta cell function.
Scandinavian journal of immunology, 1998We have previously shown that some of the DN alphabeta+ T cells arising in TcR alpha-chain transgenic mice are of gammadelta T cell origin, based on phenotypic data and on their status of TcR gene rearrangements. In the present report we investigated the impact of alphabeta TcR expression on the functional programme of the mature gammadelta precursor ...
M, Fritsch, F, Ivars
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Antigen recognition by gammadelta T cells.
Immunological reviews, 2007gammadelta T cells contribute to host immune competence uniquely. This is most likely because they have distinctive antigen-recognition properties. While the basic organization of gammadelta T-cell receptor (TCR) loci is similar to that of alphabeta TCR loci, there is a striking difference in how the diversity of gammadelta TCRs is generated ...
Yueh-hsiu, Chien, Yves, Konigshofer
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Heterogeneity of avian gammadelta T cells.
Veterinary immunology and immunopathology, 2008gammadelta T cells are distinct with respect to tissue localisation, phenotype and biological functions and similarities between species are not very apparent. To elucidate local and functional heterogeneity of non-stimulated avian gammadelta T cells, the CD8-characterised gammadelta T cell subsets [CD8alpha(+high) (CD8alphaalpha(+) and CD8alphabeta(+))
Jana, Pieper +2 more
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Immunoregulation in the tissues by gammadelta T cells.
Nature reviews. Immunology, 2003For a T-cell subset to be classified as immunoregulatory, it might reasonably be predicted that in its absence, animals would experience pathological immune dysregulation. Moreover, reconstitution of the subset should restore normal immune regulation.
Hayday, A, Tigelaar, R
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Development and selection of gammadelta T cells.
Immunological reviews, 2007Two main lineages of T cells develop in the thymus: those that express the alphabeta T-cell receptor (TCR) and those that express the gammadelta TCR. Whereas the development, selection, and peripheral localization of newly differentiated alphabeta T cells are understood in some detail, these processes are less well characterized in gammadelta T cells ...
Na, Xiong, David H, Raulet
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Gammadelta T cells: an alternative type of professional APC.
Trends in immunology, 2006A subtype of activated human gammadelta T cells, termed Vdelta2+ T cells, has antigen-presentation features similar in potency and efficacy to those seen in dendritic cells. Comparable treatment of alphabeta T cells does not result in 'professional' antigen presenting cells (APCs). What is so special about Vdelta2+ T cells?
Moser, Bernhard, Brandes, Marlène
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Cutaneous biology of gammadelta T cells.
Advances in dermatology, 2004The vast majority of serious noninfectious skin diseases are the result of inappropriate inflammatory responses (eg, atopic dermatitis, psoriasis) or neoplastic transformation (eg, squamous cell carcinoma, melanoma, cutaneous T-cell lymphoma). T cells are critical to both of these major disease categories, playing critical roles in driving or ...
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