Results 171 to 180 of about 8,798 (217)

Function of intestinal gammadelta T cells.

Immunologic research, 2000
Mucosal tissues including the intestine, lung, reproductive tract, and skin form the major interfaces between the outside and internal milieus. Facing the outside is an epithelial cell layer, the epithelium, built on a vascular connective surface. In addition to performing specialized functions, mucosal tissues are sites where immune, epithelial, and ...
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gammadelta T cells in malaria infections.

Parasitology today (Personal ed.), 2005
The association of a pronounced gammadelta T-cell response with Plasmodium infections is intriguing. The ability of parasite material to activate gammadelta T cells in vitro, and the localization of these cells in vivo in the red pulp of the spleen, suggests that these cells could play a role in the killing of bloodstage malaria parasites. However, the
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Generation of human gammadelta T-cell repertoires.

Critical reviews in immunology, 2000
The nature of how the human gammadelta T-cell repertoire is generated during normal development is poorly understood. Unlike TCR -alphabeta+ cells that are almost exclusively dependent upon the thymus for their development and maturation, gammadelta T cells can be generated in extrathymic sites.
L D, McVay, S R, Carding
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Development and selection of gammadelta T cells.

Immunological reviews, 2007
Two main lineages of T cells develop in the thymus: those that express the alphabeta T-cell receptor (TCR) and those that express the gammadelta TCR. Whereas the development, selection, and peripheral localization of newly differentiated alphabeta T cells are understood in some detail, these processes are less well characterized in gammadelta T cells ...
Na, Xiong, David H, Raulet
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Cutaneous biology of gammadelta T cells.

Advances in dermatology, 2004
The vast majority of serious noninfectious skin diseases are the result of inappropriate inflammatory responses (eg, atopic dermatitis, psoriasis) or neoplastic transformation (eg, squamous cell carcinoma, melanoma, cutaneous T-cell lymphoma). T cells are critical to both of these major disease categories, playing critical roles in driving or ...
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Gammadelta T cells: functional plasticity and heterogeneity.

Nature reviews. Immunology, 2002
Gammadelta T cells remain an enigma. They are capable of generating more unique antigen receptors than alphabeta T cells and B cells combined, yet their repertoire of antigen receptors is dominated by specific subsets that recognize a limited number of antigens. A variety of sometimes conflicting effector functions have been ascribed to them, yet their
Carding, Simon R, Egan, Paul J
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gammadelta T-cell lymphomas: a homogeneous entity?

Histopathology, 2000
gammadelta T-cells comprise an immunologically distinct lymphoid population, characterized by specific morphological, phenotypical and functional properties. Therefore it seems reasonable to speculate that neoplasms derived from this particular T-cell subset display distinct features.
C, de Wolf-Peeters, R, Achten
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Gammadelta T cells and Mycobacterium tuberculosis.

Microbes and infection, 2000
Since the first descriptions of mycobacterial reactivity for gammadelta T cells in 1989, studies of gammadelta T-cell responses to M. tuberculosis in humans and animal models have increased our understanding of the complex role(s) of this T-cell subset not only in the immune response to M.
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Gammadelta T Cells: Unconventional T Cells Involved in IBD Pathogenesis

Digestive Diseases and Sciences, 2018
Ignacio, Catalan-Serra, Juan Carlos, Andreu-Ballester, Torunn, Bruland, Arne Kristian, Sandvik   +3 more
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gammadelta T cells develop independently of Aire.

Cellular immunology, 2009
Mutations in the transcriptional regulator Aire disrupt thymic alphabeta T cell selection, causing in humans Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). However, it is not known whether Aire is needed for normal gammadelta T cell development.
Heli, Tuovinen, Nora, Pöntynen, Mikhail, Gylling, Eliisa, Kekäläinen, Jaakko, Perheentupa, Aaro, Miettinen, T Petteri, Arstila   +6 more
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