Results 11 to 20 of about 4,786 (145)
Frontiers in Pharmacology, 2020 We present the case of a kidney transplant patient (Cockroft-Gault estimated creatinine clearance 14 ml/min) who was inadvertently eight-fold overdosed with a single dose of 500 mg intravenous ganciclovir.
Verena Gotta +6 more
doaj +1 more source
Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir [PDF]
Antimicrobial Agents and Chemotherapy, 1991 Cytomegalovirus strains with reduced in vitro susceptibilities to ganciclovir have been recovered from patients who failed long-term ganciclovir therapy. The ganciclovir-resistant clinical isolates in this study were unable to induce ganciclovir phosphorylation in virus-infected cells.
Sylvia C. Stanat +5 more
openaire +3 more sources
Microbiology Spectrum, 2022 Cytomegalovirus infection during antiviral prophylaxis occurs in transplant recipients despite individualized regimens based on renal function. Fifty kidney transplant recipients were assessed between 2016 and 2019 for valganciclovir dosing, ganciclovir ...
Diana D. Wong +10 more
doaj +1 more source
Intra-cameral level of ganciclovir gel, 0.15% following topical application for cytomegalovirus anterior segment infection: A pilot study. [PDF]
PLoS ONE, 2018 To investigate the intra-cameral level of ganciclovir following topical application of ganciclovir gel, 0.15% for cytomegalovirus (CMV) anterior segment infection.Non-randomized, prospective, interventional clinical study.Patients with active CMV ...
Samanthila Waduthantri +2 more
doaj +1 more source
Pharmaceutics, 2021 In this study, Retina-RPE-Choroid-Sclera (RCS) and RPE-Choroid-Sclera (CS) were prepared by scraping them off neural retina, and using the Ussing chamber we measured the average time–concentration values in the acceptor chamber across five isolated ...
Hyeong Min Kim +6 more
doaj +1 more source
Sari Pediatri, 2020 Latar belakang. Infeksi Cytomegalovirus (CMV) merupakan penyebab tersering infeksi kongenital anak di negara berkembang. Infeksi ini dapat menyebabkan tuli sensorineural (SNHL) dan gangguan perkembangan.
Agung Triono +4 more
doaj +1 more source
Population Pharmacokinetics and Dose Optimization of Ganciclovir in Critically Ill Children
Frontiers in Pharmacology, 2021 Objective: The present study aims to establish a population pharmacokinetic model of ganciclovir and optimize the dosing regimen in critically ill children suffering from cytomegalovirus related disease.Methods: A total of 104 children were included in ...
SiChan Li +4 more
doaj +1 more source
A Case of Severe Ganciclovir-Induced Encephalopathy
Case Reports in Neurology, 2013 Background: Ganciclovir, a drug against cytomegalovirus (CMV) infection, is generally well tolerated, but can cause neurotoxicity such as encephalopathy.
Hikaru Sakamoto +8 more
doaj +1 more source
Comparison of intravitreal ganciclovir monotherapy and combination with foscarnet as initial therapy for cytomegalovirus retinitis [PDF]
International Journal of Ophthalmology, 2018 AIM: To compare the effectiveness between multiple intravitreal injections of ganciclovir alone and combined with foscarnet as initial treatment for patients with newly-onset cytomegalovirus retinitis (CMVR). METHODS: The retrospective study observed 37
Jing-Jing Fan, Yong Tao, De-Kuang Hwang
doaj +1 more source
Cytomegalovirus retinitis successfully treated with ganciclovir implant in a patient with blood ganciclovir resistance and ocular ganciclovir sensitivity [PDF]
Eye, 2012 Cytomegalovirus retinitis successfully treated with ganciclovir implant in a patient with blood ganciclovir resistance and ocular ganciclovir ...
N K Bakshi +5 more
openaire +2 more sources