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A dual fluorescent-Raman bioorthogonal probe for specific biosynthetic labeling of intracellular gangliosides. [PDF]

open access: yesCommun Chem
Mukherjee MM   +6 more
europepmc   +1 more source

Total chemical synthesis of pentameric cholera toxin subunit B.

open access: yesChem Commun (Camb)
Spaltenstein P   +4 more
europepmc   +1 more source
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Ganglioside-Storage Diseases

New England Journal of Medicine, 1971
For almost 100 years Tay-Sachs disease was the only ganglioside storage disease known. A second inborn error of ganglioside metabolism, generalized gangliosidosis, was discovered in 1965.13,35 Three additional ganglioside storage diseases have recently been uncovered,4,3,52,66,74 bringing the total to five.36 Of these, three involve storage of ...
exaly   +4 more sources

Gangliosides and hearing

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
Severe auditory impairment observed in GM3 synthase-deficient mice and humans indicates that glycosphingolipids, especially sialic-acid containing gangliosides, are indispensable for hearing. Gangliosides associate with glycoproteins to form membrane microdomains, the composition of which plays a special role in maintaining the structural and ...
Jin-Ichi, Inokuchi   +3 more
openaire   +2 more sources

Gangliosides of Melanoma

The Journal of Dermatology, 1992
AbstractThe relationships between the ganglioside composition of melanomas and their biologic behavior were investigated. (1) The amount of GM2 and/or GD2 in melanoma cells injected into nude mice correlated with the tumor growth rate. (2) GD2 content of melanoma cell lines correlated with sensitivity to radiation and vincristine. (3) GM2 expression of
T, Tsuchida, Y, Ishibashi
openaire   +2 more sources

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