Results 111 to 120 of about 9,249 (183)

Ganglioside Regulation of AMPA Receptor Trafficking

, 2014
Gangliosides are major cell-surface determinants on all vertebrate neurons. Human congenital disorders of ganglioside biosynthesis invariably result in intellectual disability and are often associated with intractable seizures. To probe the mechanisms of
Yoo, Seung-Wan, Cole, Robert N., Dawson, Ted M., Huganir, Richard L., Schnaar, Ronald L., Umanah, George K.E., Lagerlöf, Olof,, Dawson, Valina L., Motari, Mary G., Prendergast, Jillian   +9 more
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Alteration in Keratinocyte Ganglioside Content in Basal Cell Carcinomas [PDF]

, 1992
We examined the ganglioside content of normal human keratinocytes and basal cell carcinomas (BCC). The total ganglioside content of the epidermis was 0.098 ± 0.01 μg lipid-bound sialic acid/mg dry weight. GM3 was the predominant ganglioside of epidermis.
Robinson, June K, Bremer, Eric G, Arnsmeier, Sheryl L, Paller, Amy S   +3 more
core   +1 more source

Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data

Frontiers in Bioinformatics
BackgroundThe disialoganglioside GD2 is a key cancer therapy target due to its overexpression in several cancers and limited presence in normal tissues. However, experimental assessment is technically challenging and not routinely available. We developed
Arsenij Ustjanzew, Arsenij Ustjanzew, Arsenij Ustjanzew, Federico Marini, Federico Marini, Federico Marini, Saskia Wagner, Arthur Wingerter, Roger Sandhoff, Jörg Faber, Jörg Faber, Jörg Faber, Claudia Paret, Claudia Paret, Claudia Paret, Claudia Paret, Claudia Paret   +16 more
doaj   +1 more source

Precursor of H-type II histo-blood group antigen and subterminal sialic acids on gangliosides are significantly implicated in cell entry and infection by a porcine P[11] rotavirus

Emerging Microbes and Infections
Rotaviruses, non-enveloped viruses with a double-stranded RNA genome, are the leading etiological pathogen of acute gastroenteritis in young children and animals. The P[11] genotype of rotaviruses exhibits a tropism for neonates.
Miaomiao Yan, Ang Su, Denise Meyer, Gleyder Roman Sosa, Henrik Fritsch, Malte Pitters, Nicole Fischer, Georg Herrler, Paul Becher   +8 more
doaj   +1 more source

Weitere Ganglioside aus Menschenhirn

, 1964
Aus Menschenhirn konnten vier noch unbekannte Ganglioside, die nur in geringer Menge vorkommen, chromatographisch abgetrennt und näher charakterisiert werden: GGal (mit 1 Galaktose + 1 Lactaminsäure), GLact (mit 1 Lactose + 1 Lactaminsäure), G′Lact (mit ...
Wiegandt, H., Kuhn, R.
core   +1 more source

Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture [PDF]

, 1990
A GM1 ganglioside derivative bearing a photoreactive nitrophenyl azide group and tritium labeled at the acetyl group of N-acetylneuraminic acid, has been administered to cultured human fibroblasts.
G. TETTAMANTI, Sandro Sonnino, Valsecchi, Manuela, Chigorno, Vanna, V. CHIGORNO, S. SONNINO, Tettamanti, Guido, D. ACQUOTTI, Domenico Acquotti, Acquotti, Domenico, M. VALSECCHI, Manuela Valsecchi, Vanna Chigorno, Sonnino, Sandro, Guido Tettamanti   +14 more
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Establishment of various ganglioside-expressing cells.

, 2018
(A) Biosynthetic pathway of gangliosides and glycolsyltransferase cDNAs used to establish various ganglioside-expressing cells. (B) Flow cytometry of ganglioside expression on GM2-, GM1-, GD3-, and GD2-expressing transfectans.
Orie Tajima (48929), Mariko Kambe (6000296), Koichi Furukawa (30035), Keiko Furukawa (48923), Kazunori Hamamura (6000299), Rika Takeuchi (3046725), Yuhsuke Ohmi (6000293), Yuki Ohkawa (48926)   +7 more
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Apprehending ganglioside diversity: a comprehensive methodological approach

, 2015
Gangliosides make a wide family of glycosphingolipids ubiquitously expressed in mammalian tissues and particularly abundant in the brain and nervous system.
Brétillon, Lionel, Sibille, Estelle, Martine, Lucy, Chaux-Picquet, Fanny, Berdeaux, Olivier, Masson, Elodie A.Y.   +5 more
core   +1 more source

NEW CHEMICAL TRENDS IN GANGLIOSIDE RESEARCH

, 1986
A report is given of recent progress in the methodology for isolation of gangliosides from natural sources, for the preparation of molecular species of gangliosides homogeneous in both the oligosaccharide and ceramide portions of the molecule, for ...
G. TETTAMANTI, L. RIBONI, A. GIULIANI, S. SONNINO, G. KIRSCHNER, D. ACQUOTTI   +5 more
core   +1 more source

Compound porcine cerebroside and ganglioside injection attenuates cerebral ischemia–reperfusion injury in rats by targeting multiple cellular processes

, 2017
Mingyang Wang,* Yi Zhang,* Lu Feng, Ji Zheng, Shujie Fan, Junya Liu, Nan Yang, Yanyong Liu, Pingping Zuo Department of Pharmacology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing ...
Wang M, Zheng J, Liu Y, Feng L, Liu J, Zhang Y, Yang N, Fan S, Zuo P   +8 more
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