Results 91 to 100 of about 38,073 (235)

Ganglioside-Lipid and Ganglioside-Protein Interactions Revealed by Coarse-Grained and Atomistic Molecular Dynamics Simulations [PDF]

, 2017
Gangliosides are glycolipids in which an oligosaccharide headgroup containing one or more sialic acids is connected to a ceramide. Gangliosides reside in the outer leaflet of the plasma membrane and play a crucial role in various physiological processes ...
De Vries, Alex H., Gu, Ruo-Xu, Ingólfsson, Helgi I, Marrink, Siewert J.; id_orcid, De Vries, Alex H.; id_orcid, Marrink, Siewert J., Tieleman, D. Peter   +6 more
core   +1 more source

Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses

European Journal of Immunology, Volume 56, Issue 10, October 2026.
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand, Samy Taouli, Dorian McIlroy   +2 more
wiley   +1 more source

Testing multiplexing capacity of combined ganglioside-influenza bead array.

, 2012
Luminex beads coated with various payloads of Brisbane H1N1 and California H1N1 hemagglutinins were tested, and beads with the payload 0.5 µg (encircled in red) was selected for the combined ganglioside-influenza bead array (a, b).
Atul Asati (139018), Anatoly Kachurin (139022), Olga Kachurina (139020)   +2 more
core   +1 more source

Serum anti-ganglioside antibodies in patients with autoimmune limbic encephalitis

, 2021
Background/aim: Ganglioside antibodies are identified not only in patients with inflammatory neuropathies but also several central nervous system disorders and paraneoplastic neuropathies.
Tüzün, Erdem, Işıldak, Şenol, Çulha Oktar, Ayla, Baştan Tüzün, Birgül, Şanlı, Elif, Tunç, Cansu, Yılmaz, Vuslat, Kürtüncü, Murat, Çokar, Ayşe Özlem, Selçuk, Özlem, IŞILDAK, ŞENOL, OKTAR, AYLA ÇULHA, YILMAZ, VUSLAT, TÜZÜN, BİRGÜL BAŞTAN, ŞANLI, ELİF, Ayla ÇULHA OKTAR, Erdem TÜZÜN, Ayşe Özlem ÇOKAR, Özlem SELÇUK, Cansu ELMAS TUNÇ, Vuslat YILMAZ, Birgül BAŞTAN TÜZÜN, Elif ŞANLI, Murat KÜRTÜNCÜ, Şenol Şenol   +24 more
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Interaction of analgesics with lecithin and ganglioside monolayers

, 1988
Using monolayers as a membrane model, the interaction of dextrometorphan, codeine and phentanyle with lecithin and ganglioside was studied. The penetration kinetics of these drugs into the monolayers were measured at 5 and 20 mN · m-1 and the results ...
Alsina, M. Asunción, García-Antón, José María, Reig Isart, Francisca, Busquets, Antonia, Valencia Parera, Gregorio   +4 more
core   +1 more source

Enzyme‐Digested Edible Bird's Nest Promotes NGF‐Induced Differentiation of PC12 Cells by Activating the TrkA‐ERK1/2‐CREB‐BDNF Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang, Xintong Wang, Huiqing Zhu, Xiaoxian Lin, Rongzi Li, Man Yuan, Baocai Xu, Dongliang Wang, Wei Xiong, Yixuan Li   +9 more
wiley   +1 more source

Ganglioside-magnetosome complex formation enhances uptake of gangliosides by cells

, 2015
Feng Guan,1 Xiang Li,1 Jia Guo,1 Ganglong Yang,1 Xiang Li2 1The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, 2Wuxi Medical School, Jiangnan University, Wuxi, People’s Republic of China ...
Li X, Yang G, Guo J, Guan F
core  

Synthesis of radioactive and photoactivable ganglioside derivatives for the study of ganglioside-protein interactions

, 2004
The procedures for the preparation of radioactive and photoactivable ganglioside derivatives have been continuously developed from 1989, when for the first time the synthesis of photoactivable tritium labeled GM1 ganglioside was presented.
S. Prioni, V.L. Chigorno, L. Mauri, A.E.G. Prinetti, S. Sonnino, N. Loberto   +5 more
core   +1 more source

Genetic and Pharmacological Targeting of Hsp72 Overexpression/Induction in an Alzheimer's Disease Mouse Model With Combined Amyloid and Tau Pathology

Journal of Neuroscience Research, Volume 104, Issue 10, October 2026.
We investigated targeting Hsp72 protein expression genetically and via a drug, in a model of combined amyloid and tau pathology. Neither approach reduced amyloid or tau or improved body composition or movement ability. Both treatments tended to slightly improve survival in male mice and anxiety‐like behavior in female mice.
J. P. S. Marshall, A. Harutyunyan, J. Ng, O. M. West, J. M. Collins, A. E. King, J. Morizzi, P. Wright, A. C. Calkin, B. G. Drew, N. C. Jones, P. A. Adlard, M. A. Febbraio, D. C. Henstridge   +13 more
wiley   +1 more source

Anti-ganglioside Autoantibodies: Farmers vs. Controls (n = 173)*.

, 2015
Anti-ganglioside Autoantibodies: Farmers vs. Controls (n = 173)*.
Jacqueline Agnew (833948), Gregory C. Gray (446990), Freya Kamel (174797), Kazim Sheikh (833950), Leora Vegosen (833946), Irving Nachamkin (833949), Patrick N. Breysse (833947), Ellen Silbergeld (30009)   +7 more
core   +1 more source