Results 81 to 90 of about 38,073 (235)

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi   +7 more
wiley   +1 more source

alfa-fucosidase-ganglioside interactions

open access: yes, 1985
alpha-L-Fucosidase, prepared in highly purified form (Mr 70 000-74 000) from Octopus hepatopancreas, was able to hydrolyse a fucose-containing ganglioside, namely Fuc-GM1 (II3NeuAc,IV2Fuc-GgOse4-Cer).
A. Giuliani   +5 more
core   +1 more source

DESIGN, SYNTHESIS, AND VALIDATION OF GANGLIOSIDE PROBES TO REVEAL GANGLIOSIDE-PROTEIN INTERACTOME [PDF]

open access: yes, 2023
Gangliosides are glycosphingolipids that contain one or more sialic acids residues. Gangliosides are present, primarily on cell surfaces of every cell and tissue type in mammals, but are most abundantly found in the brain.
Porter, Mitchell
core   +1 more source

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

open access: yesToxins, 2020
Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further
Jonathan R. Davies   +2 more
doaj   +1 more source

Phospholipid Monolayers and Vesicular Membranes Show Only Minor Structural Changes After Interaction With α$\alpha$‐Synuclein at Low and Physiological Concentrations

open access: yesChemPhysChem, Volume 27, Issue 20, 28 October 2026.
The interaction of α$\alpha$‐synuclein with lipid membranes in the synapse is intensively discussed in view of pathologies of neurodegeneration. By X‐ray diffraction from monolayer, lipid vesicles, and synaptic vesicles at different α$\alpha$‐synuclein concentrations, structural changes of the membrane can be probed in response to the interaction.
András Major   +12 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

Isolation and characterization of ganglioside GM1b from normal human brain.

open access: yesJournal of Lipid Research, 1987
A sialidase-susceptible monosialoganglioside was isolated from normal human brain by DEAE-Sephadex A-25 and Iatrobeads column chromatography. The yield of this ganglioside was about 6 mg per whole brain.
T Ariga, R K Yu
doaj   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang   +3 more
wiley   +1 more source

Lipid domains in the membrane : thermotropic properties of sphingomyelin vesicles containing GM1 ganglioside and cholesterol

open access: yes, 1997
The thermotropic behavior of palmitoylsphingomyelin vesicles containing GM1 ganglioside and cholesterol has been investigated by high-sensitivity differential scanning calorimetry.
P. Palestini   +3 more
core   +1 more source

Altered ganglioside metabolism in inflammatory bowel disease and the impact of dietary ganglioside intake [PDF]

open access: yes, 2014
Gangliosides are integral to the structure and function of the plasma membrane. Ganglioside composition of the small intestinal brush border membrane and apical surface of the colon influence numerous cell processes including microbial attachment, cell ...
Miklavcic, John J
core   +1 more source

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