Results 81 to 90 of about 27,823 (179)

C18:3-GM1a induces apoptosis in Neuro2a cells: enzymatic remodeling of fatty acyl chains of glycosphingolipids

Journal of Lipid Research, 2005
GM1a [Galβ1-3GalNAcβ1-4(NeuAcα2-3)Galβ1-4Glcβ1-1Cer] is known to support and protect neuronal functions. However, we report that α-linolenic acid-containing GM1a (C18:3-GM1a), which was prepared using the reverse hydrolysis reaction of sphingolipid ...
Tetsuto Nakagawa, Akio Morotomi, Motohiro Tani, Noriyuki Sueyoshi, Hironobu Komori, Makoto Ito   +5 more
doaj   +1 more source

Precursor of H-type II histo-blood group antigen and subterminal sialic acids on gangliosides are significantly implicated in cell entry and infection by a porcine P[11] rotavirus

Emerging Microbes and Infections
Rotaviruses, non-enveloped viruses with a double-stranded RNA genome, are the leading etiological pathogen of acute gastroenteritis in young children and animals. The P[11] genotype of rotaviruses exhibits a tropism for neonates.
Miaomiao Yan, Ang Su, Denise Meyer, Gleyder Roman Sosa, Henrik Fritsch, Malte Pitters, Nicole Fischer, Georg Herrler, Paul Becher   +8 more
doaj   +1 more source

Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease

Neurobiology of Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease that accounts for two-thirds of all dementia cases, and age is the strongest risk factor. In addition to the amyloid hypothesis, lipid dysregulation is now recognized as a core component
Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead   +3 more
doaj   +1 more source

Gangliosides [PDF]

, 2013
Phil Livingston, Govind Ragupathi
openaire   +2 more sources

The Influence of Lipid Electric Charge on the Binding of Aβ(1–42) Amyloid Peptide to Bilayers in the Liquid-Ordered State

Biomolecules
The amyloidogenic Aβ peptides are widely considered as a pathogenic agent in Alzheimer’s disease. Aβ(1-42) would form aggregates of amyloid fibrils on the neuron plasma membranes, thus perturbing neuronal functionality.
Hasna Ahyayauch, Massimo E. Masserini, Félix M. Goñi, Alicia Alonso   +3 more
doaj   +1 more source

Expression of GD2 and GD3 in peripheral neuroblastic tumors

Indian Journal of Pathology and Microbiology
Purpose: The aim of this study was to explore the correlation between the expression of GD2 and GD3 and the histopathological types, risk groups, and chemotherapy in peripheral neuroblastic tumors (pNTs) and provide a theoretical basis for the selection ...
Xia Wei, Shaomei Li, Yizhen Wang
doaj   +1 more source

Ganglioside [PDF]

, 2020
openaire   +1 more source

Forgotten Gangliosides: <i>O</i>-Acetylated and Lactone Gangliosides. [PDF]

Int J Mol Sci
Mauri L, Vaghi S, Sonnino S.
europepmc   +1 more source

Gangliosides in molecular interactions and cell regulation. [PDF]

J Biol Chem
Mlinac-Jerkovic K, Heffer M, Schnaar RL.
europepmc   +1 more source

B4Galnt1 Deficiency Reverses Severe Neurological Symptoms in a Mouse Model of Tay-Sachs Disease. [PDF]

Neuromolecular Med
Yanbul S, Calıskan TU, Turali MC, Seyrantepe V.   +3 more
europepmc   +1 more source