Results 81 to 90 of about 38,073 (235)
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi +7 more
wiley +1 more source
alfa-fucosidase-ganglioside interactions
alpha-L-Fucosidase, prepared in highly purified form (Mr 70 000-74 000) from Octopus hepatopancreas, was able to hydrolyse a fucose-containing ganglioside, namely Fuc-GM1 (II3NeuAc,IV2Fuc-GgOse4-Cer).
A. Giuliani +5 more
core +1 more source
DESIGN, SYNTHESIS, AND VALIDATION OF GANGLIOSIDE PROBES TO REVEAL GANGLIOSIDE-PROTEIN INTERACTOME [PDF]
Gangliosides are glycosphingolipids that contain one or more sialic acids residues. Gangliosides are present, primarily on cell surfaces of every cell and tissue type in mammals, but are most abundantly found in the brain.
Porter, Mitchell
core +1 more source
Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further
Jonathan R. Davies +2 more
doaj +1 more source
The interaction of α$\alpha$‐synuclein with lipid membranes in the synapse is intensively discussed in view of pathologies of neurodegeneration. By X‐ray diffraction from monolayer, lipid vesicles, and synaptic vesicles at different α$\alpha$‐synuclein concentrations, structural changes of the membrane can be probed in response to the interaction.
András Major +12 more
wiley +1 more source
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Isolation and characterization of ganglioside GM1b from normal human brain.
A sialidase-susceptible monosialoganglioside was isolated from normal human brain by DEAE-Sephadex A-25 and Iatrobeads column chromatography. The yield of this ganglioside was about 6 mg per whole brain.
T Ariga, R K Yu
doaj +1 more source
Ciliary Membrane Lipid Homeostasis in Health and Disease
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang +3 more
wiley +1 more source
The thermotropic behavior of palmitoylsphingomyelin vesicles containing GM1 ganglioside and cholesterol has been investigated by high-sensitivity differential scanning calorimetry.
P. Palestini +3 more
core +1 more source
Altered ganglioside metabolism in inflammatory bowel disease and the impact of dietary ganglioside intake [PDF]
Gangliosides are integral to the structure and function of the plasma membrane. Ganglioside composition of the small intestinal brush border membrane and apical surface of the colon influence numerous cell processes including microbial attachment, cell ...
Miklavcic, John J
core +1 more source

