Results 101 to 110 of about 38,073 (235)

Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data

Frontiers in Bioinformatics
BackgroundThe disialoganglioside GD2 is a key cancer therapy target due to its overexpression in several cancers and limited presence in normal tissues. However, experimental assessment is technically challenging and not routinely available. We developed
Arsenij Ustjanzew, Arsenij Ustjanzew, Arsenij Ustjanzew, Federico Marini, Federico Marini, Federico Marini, Saskia Wagner, Arthur Wingerter, Roger Sandhoff, Jörg Faber, Jörg Faber, Jörg Faber, Claudia Paret, Claudia Paret, Claudia Paret, Claudia Paret, Claudia Paret   +16 more
doaj   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Hill-Waud Equation Fitting Parameters for various ganglioside compositions.

, 2016
Hill-Waud Equation Fitting Parameters for various ganglioside compositions.
Pratik Krishnan (2608471), Joshua D. Weatherston (2608477), Nolan C. Worstell (2608474), Hung-Jen Wu (184724)   +3 more
core   +1 more source

Precursor of H-type II histo-blood group antigen and subterminal sialic acids on gangliosides are significantly implicated in cell entry and infection by a porcine P[11] rotavirus

Emerging Microbes and Infections
Rotaviruses, non-enveloped viruses with a double-stranded RNA genome, are the leading etiological pathogen of acute gastroenteritis in young children and animals. The P[11] genotype of rotaviruses exhibits a tropism for neonates.
Miaomiao Yan, Ang Su, Denise Meyer, Gleyder Roman Sosa, Henrik Fritsch, Malte Pitters, Nicole Fischer, Georg Herrler, Paul Becher   +8 more
doaj   +1 more source

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

MedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng, Qi Qin, Fang Wang, Kaiyuan Zhang, Zhihua Li, Junlei Chang, Min Yu, Fuyou Guo   +7 more
wiley   +1 more source

Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review

, 2019
Ganglioside GM1 is a member of the ganglioside family which has been used in many countries and is thought of as a promising alternative treatment for preventing several neurological diseases, including cerebral ischemic injury.
Zhang, Wenchao, Li, Li, Krafft, Paul R., Wang, Tianlong, Zhang, John H., Tang, Jiping   +5 more
core   +1 more source

Anti‐idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Broadly neutralizing antibodies (bNAbs) provide insights for developing universal influenza vaccines through their ability to neutralize diverse viral strains. However, designing antigens that reliably elicit bNAb responses remains challenging due to the difficulty in targeting conserved epitopes with a single antigen.
Hiroshi Itou, Kaori Sano, Akira Ainai, Kazushige Otsuki, Toshikazu Inoue, Takuya Hemmi, Hideki Hasegawa, Tadaki Suzuki   +7 more
wiley   +1 more source

Bovine lactoferrin decreases cholera-toxin-induced intestinal fluid accumulation in mice by ganglioside interaction. [PDF]

, 2013
RIVERA, Fulton P., MEDINA, Anicia M., BEZADA, Sandra [et al.]. Bovine lactoferrin decreases cholera-toxin-induced intestinal fluid accumulation in mice by ganglioside interaction. PLOS ONE [en línea]. 2013, vol. 8, no. 4, p. 1-8. ISSN 1932-6203.Secretory
Medina, Anicia M., Theresa J Ochoa, Anicia M Medina, Roberto Valencia, Meza, Rina., Ochoa, Theresa J., Bezada, Sandra., Sandra Bezada, Ryan C Maves, Valencia, Roberto., Maves, Ryan C., Rina Meza, Fulton P Rivera, Rivera, Fulton P., Bernal, María., María Bernal, Valencia, Roberto, Ochoa Theresa J., Bernal, María, Bernal María, Valencia Roberto, Maves Ryan C., Rivera Fulton P., Bezada, Sandra, Bezada Sandra, Meza, Rina, Medina Anicia M., Ochoa Woodell, Theresa Jean, Meza Rina   +28 more
core   +1 more source

Nerve Ultrasound Features of Peripheral Nervous System Lymphoma and Non‐Systemic Vasculitic Neuropathy

European Journal of Neurology, Volume 33, Issue 10, October 2026.
Nerve ultrasound distinguishes peripheral nervous system lymphoma (PNSL) from non‐systemic vasculitic neuropathy (NSVN). PNSL shows severe focal, persistent enlargement on the initially affected side with frequent cranial/root involvement; NSVN presents milder, variable, and contralateral‐predominant enlargement, especially in newly involved nerves ...
Huihong Tian, Nan Hu, Jianfeng Ding, Min Qian, Yiying Wang, Liying Cui, Jingwen Niu, Mingsheng Liu   +7 more
wiley   +1 more source

Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury

, 2008
Autoimmune neuropathies are frequently associated with pathogenic anti-ganglioside antibodies targeting ganglioside-rich neuronal and glial membranes.
Speak, AO, Platt, FM, Greenshields, K, Willison, HJ, Goodyear, C, Townson, K   +5 more
core   +1 more source