Results 71 to 80 of about 38,073 (235)
Insights into Novel Infant Milk Formula Bioactives
Jordan Skolnick,1 Claire Chou,1 John Miklavcic1,2 1Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA; 2School of Pharmacy, Chapman University, Irvine, CA 92618, USACorrespondence: John MiklavcicSchmid College of Science ...
Skolnick J, Chou C, Miklavcic J
doaj
Background Chimeric antigen receptor (CAR)-engineered T cells have demonstrated promising clinical efficacy in patients with B cell lymphoma. However, the application of CAR-T cell therapy in the treatment of other solid tumors has been limited.
Jiayi Yu +13 more
doaj +1 more source
Sphingolipids: membrane microdomains in brain development, function and neurological diseases [PDF]
Sphingolipids are highly enriched in the nervous system where they are pivotal constituents of the plasma membranes and are important for proper brain development and functions. Sphingolipids are not merely structural elements, but are also recognized as
Anne S. B. Olsen, Nils J. Færgeman
doaj +1 more source
Weitere Ganglioside aus Menschenhirn
Aus Menschenhirn konnten vier noch unbekannte Ganglioside, die nur in geringer Menge vorkommen, chromatographisch abgetrennt und näher charakterisiert werden: GGal (mit 1 Galaktose + 1 Lactaminsäure), GLact (mit 1 Lactose + 1 Lactaminsäure), G′Lact (mit ...
Wiegandt, H., Kuhn, R.
core +1 more source
ABSTRACT The diagnosis of Guillain–Barré syndrome (GBS) relies on evolving clinical features, supported by cerebrospinal fluid (CSF), laboratory investigations, and electrodiagnostic studies. Early investigations may be nondiagnostic and should not delay treatment when progressive neurological deterioration raises clinical suspicion of GBS.
Rhiana Pereira‐Lindley +2 more
wiley +1 more source
The effect of ganglioside on diabetic neurogenic bladder [PDF]
The effect of ganglioside was studied in 6 diabetic patients with neurogenic bladder. Ganglioside is glycosphingolipids which seems to be involved in the processes of nerve growth, regeneration and tissue reinnervation.
安本, 亮二 +2 more
core
Characterization of GM1 ganglioside by direct inlet chemical ionization mass spectrometry.
Intact permethylated and permethylated-reduced (LiAlH4) derivatives of GM1 ganglioside were analyzed by direct inlet ammonia chemical ionization (CI) mass spectrometry. In addition, the trimethylsilylated derivative of the permethylated-reduced sample of
T Ariga +4 more
doaj +1 more source
Structural dynamics and pH‐regulated membrane binding of the TRAF2‐NC trimer
Abstract Tumor necrosis factor receptor‐associated factor 2 (TRAF2) is a key adaptor in TNF receptor‐signaling that operates as a trimeric assembly. Here we investigate the structural and functional properties of a TRAF2 construct spanning the trimerization and receptor‐binding domains (TRAF2‐NC, residues 266–501).
Federica Cossu +9 more
wiley +1 more source
Establishment of various ganglioside-expressing cells.
(A) Biosynthetic pathway of gangliosides and glycolsyltransferase cDNAs used to establish various ganglioside-expressing cells. (B) Flow cytometry of ganglioside expression on GM2-, GM1-, GD3-, and GD2-expressing transfectans.
Orie Tajima (48929) +7 more
core +1 more source
GM2-gangliosidosis, AB variant is an extremely rare autosomal recessive inherited disorder caused by mutations in the GM2A gene that encodes GM2 ganglioside activator protein (GM2AP).
Carla Martins +6 more
doaj +1 more source

