Results 81 to 90 of about 79,768 (305)

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells

Frontiers in Cell and Developmental Biology, 2022
Phenotypic switching between contractile (differentiated state) and proliferative (dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark of vascular remodeling that contributes to atherosclerotic diseases.
Norihiko Sasaki, Kazumi Hirano, Yuuki Shichi, Yoko Itakura, Toshiyuki Ishiwata, Masashi Toyoda   +5 more
doaj   +1 more source

Neuromuscular synaptic transmission in aged ganglioside-deficient mice [PDF]

, 2011
Gangliosides are sialylated glycosphingolipids that are present in high density on neuronal membranes, especially at synapses, where they are assumed to play functional or modulating roles.
Furukawa, K., Furukawa, K., Jacobs, B.C., Plomp, J.J., Todorov, B., Verschuuren, J.J., Willison, H.J., Zitman, F.M.P.   +7 more
core   +1 more source

Alkali-labile gangliosides

Glycoconjugate Journal, 2023
AbstractThe structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac2, and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical
Laura Mauri, Sandro Sonnino
openaire   +2 more sources

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network

Journal of Cell Biology, 2005
Mutations in GDAP1 lead to severe forms of the peripheral motor and sensory neuropathy, Charcot-Marie-Tooth disease (CMT), which is characterized by heterogeneous phenotypes, including pronounced axonal damage and demyelination.
Axel Niemann, M. Ruegg, Veronica La Padula, A. Schenone, U. Suter   +4 more
semanticscholar   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Biology of the BKPyV: An Update

Viruses, 2017
The BK virus (BKPyV) is a member of the Polyomaviridae family first isolated in 1971. BKPyV causes frequent infections during childhood and establishes persistent infections with minimal clinical implications within renal tubular cells and the urothelium.
Francois Helle, Etienne Brochot, Lynda Handala, Elodie Martin, Sandrine Castelain, Catherine Francois, Gilles Duverlie   +6 more
doaj   +1 more source

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

Toxins, 2020
Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further
Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark   +2 more
doaj   +1 more source

Membrane fusion of secretory vesicles and liposomes Two different types of fusion [PDF]

, 1981
Secretory vesicles isolated from adrenal medulla were found to fuse in vitro in response to incubation with Ca2+. Intervesicular fusion was detected by electron microscopy and was indicated by the appearance of twinned vesicles in freeze-fractured ...
Akhong, Amsterdam, Aunis, Bach, Bachmann, Baker, Baker, Bartlett, Bashford, Behr, Berger, Bretscher, Buckland, Chandler, Chi, Dahl, Dahl, Dahl, Dahl, Dahl, De Virgilis, Dean, Dipolo, Douglas, Douglas, Dreyfus, Dunham, Edwards, Ekerdt, Ekholm, Farquhar, Fenwick, Folch, Fretten, Gilkey, Gratzl, Gratzl, Gratzl, Gratzl, Hendrickson, Hockstra, Holz, Hsu, Ingolia, Koter, Lagunoff, Lawson, Liao, Llinas, Lowry, Marsh, Miledi, Miller, Milutinovic, Morris, Morris, Morris, Morris, Normann, Orci, Palade, Papahadjopoulos, Papahadjopoulos, Papahadjopoulos, Portis, Poste, Rohlich, Schober, Shinitzky, Simon, Sun, Tamaka, Vanderbosch, Voyta, Wilschut, Winkler, Winkler, Zwaal   +77 more
core   +1 more source